NCT04611620 is a clinical trial of Cognitive Dysfunction in Survivorship, sponsored by Indiana University.

Who is sponsoring NCT04611620?

NCT04611620 is sponsored by Indiana University.

What drugs are being tested in NCT04611620?

Interventions in NCT04611620: Cognitive Dysfunction.

What condition does NCT04611620 study?

NCT04611620 studies Survivorship, Cognitive Dysfunction, Pain, Depression, Anxiety, Fatigue, Sleep Disturbance.

Is NCT04611620 still recruiting?

NCT04611620 is currently completed. Last updated 22 February 2023.

Last reviewed 2023-02-22 · How we verify

NCT04611620

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Biobehavioral Correlates of Cancer-related Cognitive Dysfunction and Its Co-occurring Symptoms

Completed Last updated 22 February 2023

What this trial tests

trial testing Cognitive Dysfunction in Survivorship in 682 participants. Completed in 27 July 2021.

Timeline

16 November 2020

Primary endpoint
12 May 2021

27 July 2021

Quick facts

Lead sponsor	Indiana University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	682
Start date	16 November 2020
Primary completion	12 May 2021
Estimated completion	27 July 2021
Sites	1 location across United States

Drugs / interventions tested

Cognitive Dysfunction

Conditions studied

Survivorship — all drugs for Survivorship →
Cognitive Dysfunction — all drugs for Cognitive Dysfunction →
Pain — all drugs for Pain →
Depression — all drugs for Depression →

Sponsor

Indiana University

Who can join

21 and older, any sex, with Survivorship or Cognitive Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This descriptive, cross-sectional study will evaulate and fully characterize factors associated with cognitive dysfunction in Breast Cancer (BCS) and Colorectal Cancer (CRC) survivors that have cognitive concerns, and factors associated with psychoneurological symptom cluster in BCS and CRC survivors.

Publications & conference data

7 peer-reviewed publications reference this trial (live from Europe PMC):

Brain-Derived Neurotrophic Factor rs6265 polymorphism is associated with severe cancer-related fatigue and neuropathic pain in female cancer survivors.
Goto T, Von Ah D, Li X, Xiang L, et al · · 2024 · cited 13× · PMID 37462904 · DOI 10.1007/s11764-023-01426-w
Associations of brain-derived neurotrophic factor rs6265 polymorphism and cognitive function in breast cancer survivors from a cross-sectional study.
Goto T, Saligan LN, Li X, Xiang L, et al · · 2024 · cited 8× · PMID 38379321 · DOI 10.1002/cam4.6975
Relationship of cancer-related fatigue with psychoneurophysiological (PNP) symptoms in breast cancer survivors.
Hsiao CP, Von Ah D, Chen MK, Saligan LN. · · 2024 · cited 7× · PMID 38039708 · DOI 10.1016/j.ejon.2023.102469
Correlates of frailty in older female cancer survivors.
Rio CJ, Saligan LN, Li X, Crouch A, et al · · 2024 · cited 6× · PMID 38104481 · DOI 10.1016/j.jgo.2023.101682
Association between Cognitive Function and Physical Function, Frailty, and Quality of Life in Older Breast Cancer Survivors.
Von Ah D, Rio CJ, Carter A, Perkins SM, et al · · 2024 · cited 4× · PMID 39123446 · DOI 10.3390/cancers16152718
Characterization of cancer survivors clustered by subjective and objective cognitive function scores.
Goto T, Saligan LN, Juneau P, Gonsalves SG, et al · · 2024 · cited 1× · PMID 39185749 · DOI 10.1002/cam4.7255
Pain and Cognitive Concerns Among Breast Cancer Survivors: The Mediating Role of Substance Use Coping.
Yang Y, Tan A, Saligan LN, Von Ah D. · · 2025 · PMID 41020303 · DOI 10.1002/cam4.71204

Verify or expand the search:

Other recruiting trials for Survivorship

Currently open trials in the same condition.

NCT07305740 — On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety · NA · recruiting
NCT07264036 — Velopharyngeal Dysfunction in Head & Neck Cancer Patients, Pilot Study · NA · recruiting
NCT07165600 — Yoga to Improve Disparities in Cancer Survivorship · NA · active not recruiting
NCT06736548 — Sleep Treatment Education Program for Cancer Survivors: STEP-Together · NA · recruiting
NCT06127784 — Survivorship After HNC: A Randomized Controlled Trial Evaluating Patient Care and Adherence to Follow-up · NA · recruiting

Other Indiana University trials

Trials by the same sponsor.

NCT07470086 — The Role of Environmental Temperatures in Respiratory Control · NA · not yet recruiting
NCT07470099 — The Role of Breathing Perception in Respiratory Control · NA · not yet recruiting
NCT07179952 — Efficacy and Safety of Slow Release Dehydroepiandrosterone (DHEA ) · Phase 2 · not yet recruiting
NCT07070804 — Maternal Biomarkers and Environmental Contributors to Autism Spectrum Disorders in Children of First-time Mothers · not yet recruiting
NCT07499583 — Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder · Phase 1, PHASE2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04611620 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Indiana University
Last refreshed: 22 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04611620.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing