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NCT04607395: R2
Pre-operative Radiograph of Deep Carious Lesions as a Predictive Tool for Pulpal Exposure
trial testing pre-operative radiograph in Deep Caries in 358 participants. Completed in 1 July 2020.
1 August 2017
Quick facts
| Lead sponsor | Hospices Civils de Lyon |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 358 |
| Start date | 1 February 2015 |
| Primary completion | 1 August 2017 |
| Estimated completion | 1 July 2020 |
| Sites | 1 location across France |
Drugs / interventions tested
- pre-operative radiograph
Conditions studied
- Deep Caries — all drugs for Deep Caries →
Sponsor
Hospices Civils de Lyon — full company profile →
Who can join
Adults 8 to 80, any sex, with Deep Caries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Preserving pulpal vitality is a major challenge when excavating deep caries lesions without severe symptomatology. Pulpal exposure alters success of the treatment (dropping from 93% for indirect pulp treatment with selective excavation to 11% for direct pulpotomy) and thus prognosis of dental organ and cost-effectiveness of the treatment. The preoperative x-ray is a complementary examination which allows to estimate the depth of the carious lesion. In clinical practice, it is currently difficult to accurately measure this depth on preoperative radiographs. This lack of precision leads to a decrease in the effective capacity of the operator to predict the risk of pulpal exposure. Their interpretation is considered imprecise and is not used as a diagnostic element. The aim of this study was to determine if the use of pre-operative retroalveolar radiographs can help to predict pulpal exposure risk.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Place of a new radiological index in predicting pulp exposure before intervention for deep carious lesions.
Gasqui MA, Pérard M, Decup F, Monsarrat P, et al · · 2022 · cited 5× · PMID 33954908 · DOI 10.1007/s11282-021-00530-w
Verify or expand the search:
- PubMed search for NCT04607395
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Deep Caries
Currently open trials in the same condition.
- NCT06293521 — Clinical and Radiographic Success Rate of Pulpotomy Versus Pulpectomy for Management of Primary Teeth With Deep Caries · Phase 2 · recruiting
- NCT06683833 — Comparison Between Egyptian MTA, Biodentine Versus Calcium Hydroxide as Indirect Pulp Capping Materials In Permanent Tee · Phase 4 · recruiting
- NCT05816525 — The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue · recruiting
- NCT06495242 — Direct Pulp Capping Compared to Partial Pulpotomy in Carious Pulp Exposures · NA · active not recruiting
Other Hospices Civils de Lyon trials
Trials by the same sponsor.
- NCT07569536 — Efficacy of the Alpha 2 Agonist Dexmedetomidine for Sympathetic Deactivation in REfractory Septic Shock · Phase 3 · not yet recruiting
- NCT07529314 — Evaluating Interventional Radiology for Cancer Pain Management · NA · not yet recruiting
- NCT07273929 — Comparative Study of the Effectiveness of Three Access Routes for Implanting an Electronic Intracardiac Device · Phase 3 · not yet recruiting
- NCT07474532 — Attitudes and Beliefs Related to Benzodiazepine Deprescribing · not yet recruiting
- NCT07313007 — Assessment of Gut Microbiota-Derived Amino Acid Metabolite Production in Patients With MASLD · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04607395 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospices Civils de Lyon
- Last refreshed: 29 October 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04607395.
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