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NCT05816525
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
trial testing Partial removal of carious tissue in Deep Caries in 100 participants. Currently enrolling.
31 December 2027
Quick facts
| Lead sponsor | University of Helsinki |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 21 April 2023 |
| Primary completion | 31 December 2027 |
| Estimated completion | 31 December 2027 |
| Sites | 1 location across Finland |
Drugs / interventions tested
- Partial removal of carious tissue
- Final restoration
Conditions studied
- Deep Caries — all drugs for Deep Caries →
- Pulpitis Reversible — all drugs for Pulpitis Reversible →
- Pulp Hyperemia — all drugs for Pulp Hyperemia →
Sponsor
University of Helsinki
Who can join
Adults 18 to 50, any sex, with Deep Caries or Pulpitis Reversible. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this prospective, observational clinical cohort study is to study the effect of the preoperative condition of the tooth on the outcome of partial removal of carious tissue in mature teeth in adults. The main questions the study aims to answer are: * Do preoperative symptoms affect the outcome? * Does the depth of the carious lesion affect the outcome? One hundred participants will be recruited. Patients who meet the eligibility criteria will be asked to give their informed consent to participate in the study. Partial carious tissue removal will be performed regardless of participation in the study because selective carious tissue removal is the standard treatment of choice for a vital tooth with a deep carious lesion according to the Finnish national treatment guidelines. Participants will be asked to fill in a questionnaire regarding symptoms 7 days post-treatment. The teeth will then be followed up for 12-24 months. The null hypothesis is that there is no difference in the success between i) deep and extremely deep carious lesions and ii) initial and mild pulpitis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05816525
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Related trials
Other recruiting trials for Deep Caries
Currently open trials in the same condition.
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- NCT06495242 — Direct Pulp Capping Compared to Partial Pulpotomy in Carious Pulp Exposures · NA · active not recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05816525 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Helsinki
- Last refreshed: 3 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05816525.
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