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NCT04492046
Complex Decongestive Applications in Patients With Lipedema
trial testing Manual Lymph Drainage in Lipedema in 23 participants. Completed in 12 February 2020.
12 February 2020
Quick facts
| Lead sponsor | Gazi University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 23 |
| Start date | 2 September 2019 |
| Primary completion | 12 February 2020 |
| Estimated completion | 12 February 2020 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Manual Lymph Drainage
- Bandaging
Conditions studied
- Lipedema — all drugs for Lipedema →
Sponsor
Gazi University
Who can join
Adults 18 to 65, any sex, with Lipedema. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Lipedema is a rare condition which almost exclusively affects women. The disease is characterized with bilateral, symmetric abnormal accumulation of subcutaneous fat and is often mistaken for simple obesity. In most patients, the hips, buttocks, thighs, knees, and lower legs are affected. Upper extremity involvement has been reported to be present in 80% patients. The hands and feet are never affected. The accumulation of subcutaneous fat and edema results in tenderness, sensitivity to touch and pressure and also pain. Patients also tend to bruise easily even after a minimal trauma. It has been reported that the complaint of pain increases with aging.There is no known cure for lipedema. However, conservative treatment with physiotherapy, manual lymph drainage and compression, also known as complex decongestive physiotherapy is used worldwide as a standard treatment regimen . The aim of this study is to investigate the effect of complex decongestive applications on lower extremity limb circumference and volume in patients with lipedema.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Effects of Complex Decongestive Physiotherapy Applications on Lower Extremity Circumference and Volume in Patients with Lipedema.
Volkan-Yazıcı M, Yazici G, Esmer M. · · 2021 · cited 11× · PMID 33124947 · DOI 10.1089/lrb.2020.0080
Verify or expand the search:
- PubMed search for NCT04492046
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Manual Lymph Drainage
Trials testing the same drug.
- NCT05976399 — Manual Lymph Drainage in Individuals With Migraine · NA · completed
Other recruiting trials for Lipedema
Currently open trials in the same condition.
- NCT07489248 — Multimodal Ultrasound for Differentiating Lymphedema and Lipedema · recruiting
- NCT07468097 — The Impact of Metabolic Status on Pain and Central Sensitization in Women With Lipedema: A Cross-Sectional Observational · recruiting
- NCT07294014 — Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema · recruiting
- NCT07458932 — Evaluation of Physical Activity in Women With Lipedema · recruiting
- NCT06558851 — The Effect of Systematic Endurance Training in Treatment of Women With Lipedema · NA · active not recruiting
Other Gazi University trials
Trials by the same sponsor.
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- NCT07471737 — Patient Safety and Medical Errors in Nursing Education: Learning by Doing and Experiencing With Simulated Patients · NA · not yet recruiting
- NCT07440563 — Auricular Vagus Nerve Stimulation Combined With Rehabilitation in Parkinson's Disease · NA · enrolling by invitation
- NCT07496398 — Median and Ulnar Nerve Function in Tattoo Artists · recruiting
- NCT07471386 — Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04492046 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gazi University
- Last refreshed: 30 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04492046.
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