Last reviewed · How we verify
NCT05976399
Manual Lymph Drainage in Individuals With Migraine
NA trial testing Connective Tissue Massage in Manual Lymphatic Drainage in 40 participants. Completed in 8 February 2021.
15 October 2020
Quick facts
| Lead sponsor | Izmir Democracy University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 6 June 2019 |
| Primary completion | 15 October 2020 |
| Estimated completion | 8 February 2021 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Connective Tissue Massage
- Manual Lymph Drainage
Conditions studied
- Manual Lymphatic Drainage — all drugs for Manual Lymphatic Drainage →
Sponsor
Izmir Democracy University
Who can join
Adults 18 to 65, any sex, with Manual Lymphatic Drainage. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In the literature, research into the examination of the effect of MLD on migraine is quite limited. Our study aimed to examine the effectiveness of manual lymph drainage and connective tissue massage treatments on neck pain and disability, sleep quality, pain threshold and severity, depression and quality of life.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison of the efficacy of connective tissue massage and manual lymphatic drainage in patients with migraine: a randomized controlled trial.
Yıldırım Bulut B, Çinar Özdemir Ö. · · 2025 · PMID 41070573 · DOI 10.22514/jofph.2025.054
Verify or expand the search:
- PubMed search for NCT05976399
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Connective Tissue Massage
Trials testing the same drug.
- NCT06135142 — Connective Tissue Massage And Classical Massage In Patients With Chronic Non-Specific Low Back Pain. · NA · completed
- NCT05202028 — The Efficacy of Massage and Reflexology Applications in Children With Cerebral Palsy · NA · unknown
- NCT04211701 — Effects of Connective Tissue Massage and Classical Massage · NA · unknown
- NCT05063188 — Connective Tissue Massage With Fibromyalgia · NA · completed
- NCT04171362 — The Effect of Connective Tissue Massage in Patients With Migraine · NA · completed
Other Izmir Democracy University trials
Trials by the same sponsor.
- NCT07511153 — Does the Cervical Stenosis Affect Hand Function? · not yet recruiting
- NCT07416097 — Comparison of Multidimensional Parameters in Women With Fibromyalgia and Healthy Controls · NA · not yet recruiting
- NCT07358702 — Sedentary Status and Multidimensional Outcomes in Fibromyalgia · NA · not yet recruiting
- NCT07396597 — Physical Impairments in Premature Ventricular Complex · not yet recruiting
- NCT07474623 — Effects of Nicotine Dependence on Multidimensional Health Outcomes · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05976399 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Izmir Democracy University
- Last refreshed: 8 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05976399.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing