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NCT04449211
The Effectiveness in the Treatment of Long Bone Defect Using 3D-printed Implant
EARLY_PHASE1 trial testing Implantation in Bone Loss in 10 participants. Currently enrolling.
1 November 2024
Quick facts
| Lead sponsor | Cho Ray Hospital |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 10 |
| Start date | 6 October 2023 |
| Primary completion | 1 November 2024 |
| Estimated completion | 30 December 2024 |
| Sites | 1 location across Vietnam |
Drugs / interventions tested
- Implantation — full drug profile →
Conditions studied
- Bone Loss — all drugs for Bone Loss →
- Defect Limb — all drugs for Defect Limb →
Sponsor
Cho Ray Hospital
Who can join
18 and older, any sex, with Bone Loss or Defect Limb. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To evaluate the effectiveness of 3D-printed titanium alloy implants in the treatment of long bone defect in adults
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Poly(lactic-<i>co</i>-glycolic acid)-based composite bone-substitute materials.
Zhao D, Zhu T, Li J, Cui L, et al · · 2021 · cited 238× · PMID 32954053 · DOI 10.1016/j.bioactmat.2020.08.016 -
Scaffold Guided Bone Regeneration for the Treatment of Large Segmental Defects in Long Bones.
Schulze F, Lang A, Schoon J, Wassilew GI, et al · · 2023 · cited 31× · PMID 36830862 · DOI 10.3390/biomedicines11020325
Verify or expand the search:
- PubMed search for NCT04449211
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Implantation
Trials testing the same drug.
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- NCT05279157 — Autologous Adipose-Derived Adult Stem Cell Implantation for Corneal Diseases (ADASCs-CT-CD) · Phase 2 · completed
- NCT05260463 — LOQTEQ® Antibacterial Pre-Market Study · NA · completed
- NCT03887494 — Study of the Impact of the Femoral Implant "Y-strut" on Lytic Bone Metastases of the Femoral Neck (WAZA-ARY) · NA · unknown
Other recruiting trials for Bone Loss
Currently open trials in the same condition.
- NCT07156110 — Prosthetic Modality and MBL · NA · recruiting
- NCT07196943 — Prospective Outcomes of Guided Equator Overdentures · recruiting
- NCT06629961 — Impact of Transepithelial Abutment Connection and Disconnection in Dental Implants · NA · recruiting
- NCT06527664 — Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN) · recruiting
- NCT04112992 — An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects · recruiting
Other Cho Ray Hospital trials
Trials by the same sponsor.
- NCT06985095 — Evaluation of a Structured Nutrition Educational Program in Insulin-treated Diabetic Patients in Vietnam · NA · recruiting
- NCT05362825 — Surgery Outcome Treated by Neo-adjuvant Combination of Oxaliplatin, Irinotecan, Folinic Acid and Fluorouracil (FOLFOXIRI · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04449211 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cho Ray Hospital
- Last refreshed: 3 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04449211.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing