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NCT05362825
Surgery Outcome Treated by Neo-adjuvant Combination of Oxaliplatin, Irinotecan, Folinic Acid and Fluorouracil (FOLFOXIRI) Regimen in Synchronous Liver Limited Metastasis Colorectal Cancer
trial testing Neo-adjuvant Chemotherapy FOLFOXIRI Regimen in Liver Metastasis Colon Cancer in 89 participants. Status unknown.
20 December 2024
Quick facts
| Lead sponsor | Cho Ray Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 89 |
| Start date | 18 February 2022 |
| Primary completion | 20 December 2024 |
| Estimated completion | 23 January 2025 |
| Sites | 1 location across Vietnam |
Drugs / interventions tested
- Neo-adjuvant Chemotherapy FOLFOXIRI Regimen — full drug profile →
- synchronous resection surgery
Conditions studied
- Liver Metastasis Colon Cancer — all drugs for Liver Metastasis Colon Cancer →
- Synchronous Neoplasm — all drugs for Synchronous Neoplasm →
Sponsor
Cho Ray Hospital
Who can join
Adults 18 to 75, any sex, with Liver Metastasis Colon Cancer or Synchronous Neoplasm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This single arm study aims to evaluate the rate of conversion therapy in patients with unresectable liver-limited metastatic colorectal cancer (mCRC) using FOLFOXIRI neoadjuvant regimen and to assess the other outcome including the response rate, the survival rate and the safety profile.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Current landscape of preoperative neoadjuvant therapies for initial resectable colorectal cancer liver metastasis.
Cheng XF, Zhao F, Chen D, Liu FL. · · 2024 · cited 7× · PMID 38515943 · DOI 10.3748/wjg.v30.i7.663 -
FOLFOXIRI for First-Line Treatment of Unresectable Colorectal Cancer with Liver Metastases in a Resource-Limited Setting.
Hao VDT, Tri PM, My DT, Anh LT, et al · · 2024 · cited 2× · PMID 39480530 · DOI 10.1007/s12029-024-01133-4 -
FOLFOXIRI for First-Line Treatment of Unresectable Colorectal Cancer with Liver Metastases in a Resource-Limited Setting
Hao VDT, Tri PM, My DT, Anh LT, et al · · 2024 · DOI 10.21203/rs.3.rs-4831430/v1
Verify or expand the search:
- PubMed search for NCT05362825
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Liver Metastasis Colon Cancer
Currently open trials in the same condition.
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- NCT06630624 — Dose Finding, Efficacy and Immunological Response of IP-001 Following MWA or IRE for CRLM · Phase 1, PHASE2 · recruiting
- NCT05775146 — SBRT of Metastases Following Neo-adjuvant Treatment for Colorectal Cancer With Synchronous Liver Metastases · Phase 2 · recruiting
- NCT06200831 — Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases · NA · recruiting
Other Cho Ray Hospital trials
Trials by the same sponsor.
- NCT06985095 — Evaluation of a Structured Nutrition Educational Program in Insulin-treated Diabetic Patients in Vietnam · NA · recruiting
- NCT04449211 — The Effectiveness in the Treatment of Long Bone Defect Using 3D-printed Implant · EARLY_PHASE1 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05362825 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cho Ray Hospital
- Last refreshed: 11 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05362825.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing