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NCT04403958: PROOF II
The Use of Proximal Carpal Row Versus Iliac Crest as Bone Graft in Total Wrist Fusion
NA trial testing PRC in Wrist Arthritis in 84 participants. Status unknown.
31 December 2023
Quick facts
| Lead sponsor | Töölö Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 84 |
| Start date | 1 September 2021 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 December 2024 |
Drugs / interventions tested
- PRC
- TWA
Conditions studied
- Wrist Arthritis — all drugs for Wrist Arthritis →
- Fusion; Joint — all drugs for Fusion; Joint →
Sponsor
Töölö Hospital
Who can join
Adults 18 to 75, any sex, with Wrist Arthritis or Fusion; Joint. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Study purpose is to compare the outcome after total wrist arthrodesis (TWA) with proximal carpal row (Proximal Row Carpectomy = PRC) as bone graft versus iliac crest cancellous bone graft. Patients with radiologically and clinically confirmed advanced osteoarthritis are randomized (1:1 computer generated sequence with random block size) to two parallel groups and will undergo either total wrist arthrodesis with PRC or TWA with iliac crest bone grafting. Baseline data is collected preoperatively and is a follow-up visits at every 6 weeks after the surgery is arranged until the wrist is fused. The primary end-point is 6 months and the primary outcome is fusion rate.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04403958
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Wrist Arthritis
Currently open trials in the same condition.
- NCT03315377 — Lunatocapitate Fusion Versus Four-corner Fusion for SNAC and SLAC Arthritis. · NA · active not recruiting
Other Töölö Hospital trials
Trials by the same sponsor.
- NCT06365710 — Physiotherapy vs Telerehabilitation After Volar Plating of Distal Radius Fracture · NA · recruiting
- NCT04826380 — Thumb Basal Joint (CMC I) Arthritis - Preoperative Anxiety/Depression, Outcome Instruments, Carpal Cinematics and Cost-u · NA · unknown
- NCT04260165 — Proximal Row Carpectomy vs Four-corner Fusion for Osteoarthritis of the Wrist · NA · recruiting
- NCT04323410 — Casting Versus Percutaneus Pinning Treatment of Pediatric Overriding Distal Forearm Fractures · NA · recruiting
- NCT04167098 — Effectiveness of Platelet-rich Plasma for Treatment of Trigger Finger · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04403958 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Töölö Hospital
- Last refreshed: 30 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04403958.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing