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NCT04167098

Effectiveness of Platelet-rich Plasma for Treatment of Trigger Finger

Status unknown NA Last updated 17 December 2020
What this trial tests

NA trial testing PRP injection in Tendon Entrapment in 117 participants. Status unknown.

Timeline
1 November 2019
Primary endpoint
1 July 2021
1 July 2022

Quick facts

Lead sponsorTöölö Hospital
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingtriple
Primary purposetreatment
Enrollment117
Start date1 November 2019
Primary completion1 July 2021
Estimated completion1 July 2022
Sites1 location across Finland

Drugs / interventions tested

Conditions studied

Sponsor

Töölö Hospital

Who can join

Adults 18 to 75, any sex, with Tendon Entrapment. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Study purpose is to evaluate the effectiveness of Platelet-rich Plasma (PRP) injection in the treatment of trigger finger. We compare PRP to a corticosteroid (methylprednisolone) injection in a prospective randomized triple-blind placebo-controlled study. Patients with clinically confirmed trigger finger are randomized (1:1:1 computer generated sequence with random block size) to three parallel groups and will receive an injection of either PRP, corticosteroid or placebo (0.9% saline) around the affected tendon sheath in a double-blind setting. Baseline data is collected and is followed by a phone call at 1 month, and follow-up visits at 3, 6, 12 and 24 months after the intervention. Unveiling of the allocation is at 6 months post-intervention. The primary outcome measures are: * Symptom resolution * Patient-Rated Wrist Evaluation Secondary outcomes: * Quick-Disabilities of the Arm, Shoulder and Hand * Pain Visual Analogue Score * Global improvement (7-step Likert-scale) * Grip strength * Finger range of motion

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Platelet-rich plasma versus corticosteroid injection for treatment of trigger finger: study protocol for a prospective randomized triple-blind placebo-controlled trial.
    Aspinen S, Nordback PH, Anttila T, Stjernberg-Salmela S, et al · · 2020 · cited 10× · PMID 33246497 · DOI 10.1186/s13063-020-04907-w

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Other trials of PRP injection

Trials testing the same drug.

Other Töölö Hospital trials

Trials by the same sponsor.

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