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NCT04392544
Intestinal Inflammation in CF Patients
trial in Cystic Fibrosis in Children in 100 participants. Participants enrolled and being followed up; not accepting new ones.
31 March 2024
Quick facts
| Lead sponsor | The Hospital for Sick Children |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 11 September 2018 |
| Primary completion | 31 March 2024 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Canada |
Conditions studied
- Cystic Fibrosis in Children — all drugs for Cystic Fibrosis in Children →
- Cystic Fibrosis Gastrointestinal Disease — all drugs for Cystic Fibrosis Gastrointestinal Disease →
- Cystic Fibrosis — all drugs for Cystic Fibrosis →
Sponsor
The Hospital for Sick Children
Who can join
10 and older, any sex, with Cystic Fibrosis in Children or Cystic Fibrosis Gastrointestinal Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cystic Fibrosis (CF) is a disease that affects salt and water transport in multiple organs. Many CF patients suffer from abdominal pain and this could be due to intestinal inflammation. However, so far we do not know how many of the CF patients actually do have intestinal inflammation when looking at intestinal specimens. There is a proven connection between chronic inflammation and developing colorectal cancer and over the years more CF patients are developing colorectal cancer. Thus, it becomes increasingly important to look for the presence of intestinal inflammation in CF patients since early treatment may improve their symptoms and reduce the risk for colorectal cancer.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04392544
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Cystic Fibrosis in Children
Currently open trials in the same condition.
- NCT06984679 — Physical Impairments in Children With Cystic Fibrosis · recruiting
- NCT06617013 — GERD in Children With Cystic Fibrosis · NA · recruiting
- NCT06284577 — Quality of Life and Gut Health in Pediatric Patients With Cystic Fibrosis · NA · recruiting
- NCT04613128 — The PROMISE Pediatric Study 6 to 11 Years Old · active not recruiting
- NCT04602468 — Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER) · Phase 4 · active not recruiting
Other The Hospital for Sick Children trials
Trials by the same sponsor.
- NCT07454681 — MRI Assessment of Lung Airways in Cystic Fibrosis: Evaluate MRI's Ability to Detect Changes in Airway Structure . · not yet recruiting
- NCT07452575 — 3D Ultrasound in Hemophilic Ankles · NA · not yet recruiting
- NCT07508826 — AI-assisted Endotracheal Intubation · NA · not yet recruiting
- NCT07345819 — Dexamethasone vs. Placebo in Children and Youth Hospitalized for Orbital Cellulitis · NA · not yet recruiting
- NCT07497178 — MRgFUS for Childhood Epilepsy · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04392544 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Hospital for Sick Children
- Last refreshed: 20 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04392544.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing