Last reviewed · How we verify
NCT06284577
Quality of Life and Gut Health in Pediatric Patients With Cystic Fibrosis
NA trial testing Multistrain Probiotic in Cystic Fibrosis in Children in 40 participants. Currently enrolling.
1 June 2027
Quick facts
| Lead sponsor | Oslo University Hospital |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 2 January 2024 |
| Primary completion | 1 June 2027 |
| Estimated completion | 1 July 2027 |
| Sites | 1 location across Norway |
Drugs / interventions tested
- Multistrain Probiotic
- Placebo - maltodextrin
Conditions studied
- Cystic Fibrosis in Children — all drugs for Cystic Fibrosis in Children →
Sponsor
Oslo University Hospital
Who can join
Adults 2 to 18, any sex, with Cystic Fibrosis in Children. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the present study is to investigate the effect of probiotic supplementation on GI related quality of life, through a randomised placebo-controlled clinical trial. Moreover, the invetigators wish to study CF microbiota and intestinal inflammation in the setting of probiotic supplementation and newly started treatment with a highly effective CF-specific treatment, elexacaftor-tezacaftor-ivacaftor (ETI). The proposed project has the potential to increase QoL and decrease GI morbidity in children with CF. If successful, the results of this study can contribute to alter the care of CF patients by including supplementation of probiotics in routine CF care. Morever, the study can provide much needed insights to GI microbiota and inflammation in pediatric CF patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06284577
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Multistrain Probiotic
Trials testing the same drug.
- NCT06088940 — The Chemo-Gut Probiotic Trial for Cancer Survivors · NA · unknown
- NCT05344352 — Effect of a Multistrain Probiotic on Allergic Rhinitis Symptoms and Gut Microbiota Composition in Atopic Patients · NA · completed
Other recruiting trials for Cystic Fibrosis in Children
Currently open trials in the same condition.
- NCT06984679 — Physical Impairments in Children With Cystic Fibrosis · recruiting
- NCT06617013 — GERD in Children With Cystic Fibrosis · NA · recruiting
- NCT04613128 — The PROMISE Pediatric Study 6 to 11 Years Old · active not recruiting
- NCT04602468 — Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER) · Phase 4 · active not recruiting
- NCT04392544 — Intestinal Inflammation in CF Patients · active not recruiting
Other Oslo University Hospital trials
Trials by the same sponsor.
- NCT07463885 — Spontaneous vs Controlled Mechanical Ventilation in Acute Hypoxemic Respiratory Failure · NA · not yet recruiting
- NCT07427719 — Retinopathy of Prematurity - Visual Function and Retinal Structure · not yet recruiting
- NCT07403331 — Severe Chronic Neuropathic Pain: A Treatment Bundle, Using Spinal Cord Stimulation and Multidisciplinary Treatment, to R · NA · recruiting
- NCT07449897 — Cholecystectomy With Intraoperative Management of Bile Duct Stones in Norway - the BILNOR Study · recruiting
- NCT06173817 — The Use of Isocapnic Hyperventilation (iHV) for Treatment of Methanol Poisoned Patients · Phase 1 · withdrawn
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06284577 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Oslo University Hospital
- Last refreshed: 13 June 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06284577.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing