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NCT04389060
Effect of Acute Dietary Supplementation With Grape Seed Extract on Aortic Stiffness, Arterial Pressure, and Blood Vessel Dilation in Collegiate Obese Individuals at Rest
NA trial testing Grape seed extract in Obesity in 20 participants. Completed in 1 March 2020.
1 March 2020
Quick facts
| Lead sponsor | California Baptist University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 20 |
| Start date | 1 March 2019 |
| Primary completion | 1 March 2020 |
| Estimated completion | 1 March 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Grape seed extract — full drug profile →
Conditions studied
- Obesity — all drugs for Obesity →
Sponsor
California Baptist University
Who can join
Adults 18 to 29, male only, with Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigated if elevated BP and aortic stiffness characterized in obese individuals are attenuated following acute grape seed extract supplementation. It is hypothesized that acute dietary supplementation with grape seed extract attenuates aortic stiffness, systolic blood pressure, diastolic blood pressure, mean arterial pressure, and total peripheral resistance and these effects are partially due to reductions in peripheral vasoconstriction
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04389060
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Grape seed extract
Trials testing the same drug.
- NCT05945771 — Effects of Acute Grape Seed Extract Supplementation on Muscle Metaboreflex in Healthy Young Individuals · NA · completed
- NCT05116150 — Effects of Combined Grape Seed Extract and L-citrulline Supplementation on Hemodynamic Responses in Young Males · NA · completed
Other recruiting trials for Obesity
Currently open trials in the same condition.
- NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
- NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
- NCT07272837 — Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass · recruiting
- NCT07481630 — A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoart · Phase 3 · recruiting
- NCT07527195 — Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscl · Phase 1 · recruiting
Other California Baptist University trials
Trials by the same sponsor.
- NCT07137988 — Effect of Acute Grape Seed Extract Supplementation on the Heart Rate Recovery in Young Individuals · NA · completed
- NCT06629337 — Effect of Aerobic Exercise with Blood Flow Restriction on Post-exercise Hypotension in Young Adults: the Role of Histami · NA · completed
- NCT05945771 — Effects of Acute Grape Seed Extract Supplementation on Muscle Metaboreflex in Healthy Young Individuals · NA · completed
- NCT06428890 — Effect of 7 Days of Grape Seed Extract Supplementation on Cold Pressor Test and Muscle Metaboreflex in Individuals With · NA · completed
- NCT04465110 — Effects of Chronic Dietary Grape Seed Extract Supplementation on Aortic Stiffness and Hemodynamic Responses to Exercise · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04389060 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by California Baptist University
- Last refreshed: 15 May 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04389060.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing