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NCT07137988
Effect of Acute Grape Seed Extract Supplementation on the Heart Rate Recovery in Young Individuals
NA trial testing 600 mg grape seed extract in Healthy Young Men in 12 participants. Completed in 31 December 2024.
3 December 2024
Quick facts
| Lead sponsor | California Baptist University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 12 |
| Start date | 3 October 2024 |
| Primary completion | 3 December 2024 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- 600 mg grape seed extract
- 600 mg Starch
Conditions studied
- Healthy Young Men — all drugs for Healthy Young Men →
Sponsor
California Baptist University
Who can join
Adults 18 to 30, male only, with Healthy Young Men. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study hypothesized that sustained sympathoexcitation via MMA slows down PHRR and that GSE supplementation is effective at improving PHRR in young individuals. 12 Participants were randomly assigned, via a double-blind, cross-over design, to either receive GSE (300mg, 2 capsules) or PL (300mg, 2 capsules), with a washout period of at least 72 hrs. between trials. A submaximal exercise test was performed using a cycle ergometer combined with isometric handgrip exercise using a handgrip dynamometer, and blood flow occlusion by placing a cuff over the brachial artery of the dominant arm. Post heart rate recovery (PHRR) was measured at 5 sec. intervals throughout the experiment. The PHRR was evaluated between GSE and PL at every min. for 300 sec.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07137988
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other California Baptist University trials
Trials by the same sponsor.
- NCT06629337 — Effect of Aerobic Exercise with Blood Flow Restriction on Post-exercise Hypotension in Young Adults: the Role of Histami · NA · completed
- NCT05945771 — Effects of Acute Grape Seed Extract Supplementation on Muscle Metaboreflex in Healthy Young Individuals · NA · completed
- NCT06428890 — Effect of 7 Days of Grape Seed Extract Supplementation on Cold Pressor Test and Muscle Metaboreflex in Individuals With · NA · completed
- NCT04465110 — Effects of Chronic Dietary Grape Seed Extract Supplementation on Aortic Stiffness and Hemodynamic Responses to Exercise · NA · completed
- NCT05116150 — Effects of Combined Grape Seed Extract and L-citrulline Supplementation on Hemodynamic Responses in Young Males · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07137988 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by California Baptist University
- Last refreshed: 22 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07137988.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing