NCT04337697 (NSR-DEV) is a clinical trial in Neonatal Seizure, sponsored by University of California, San Francisco.

Who is sponsoring NCT04337697?

NCT04337697 is sponsored by University of California, San Francisco.

What condition does NCT04337697 study?

NCT04337697 studies Neonatal Seizure, Hypoxic-Ischemic Encephalopathy, Stroke, Intracranial Hemorrhages, Epilepsy, Cerebral Palsy, Intellectual Disability.

Is NCT04337697 still recruiting?

NCT04337697 is currently completed. Last updated 5 February 2026.

Last reviewed 2026-02-05 · How we verify

NCT04337697: NSR-DEV

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Neonatal Seizure Registry - Developmental Functional EValuation

Completed Last updated 5 February 2026

What this trial tests

trial in Neonatal Seizure in 188 participants. Completed in 1 March 2025.

Timeline

15 March 2020

Primary endpoint
28 February 2025

1 March 2025

Quick facts

Lead sponsor	University of California, San Francisco
Status	Completed
Study type	OBSERVATIONAL
Enrollment	188
Start date	15 March 2020
Primary completion	28 February 2025
Estimated completion	1 March 2025
Sites	9 locations across United States

Conditions studied

Neonatal Seizure — all drugs for Neonatal Seizure →
Hypoxic-Ischemic Encephalopathy — all drugs for Hypoxic-Ischemic Encephalopathy →
Stroke — all drugs for Stroke →
Intracranial Hemorrhages — all drugs for Intracranial Hemorrhages →

Sponsor

University of California, San Francisco

Who can join

Adults 2 to 8, any sex, with Neonatal Seizure or Hypoxic-Ischemic Encephalopathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The NSR-DEV study is a longitudinal cohort study of around 280 Neonatal Seizure Registry participants that aims to evaluate childhood outcomes after acute symptomatic neonatal seizures, as well as examine risk factors for developmental disabilities and whether these are modified by parent well-being.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Toward Equity in Research Participation: Association of Financial Impact With In-Person Study Participation.
Shellhaas RA, Lemmon ME, Gosselin BN, Sturza J, et al · · 2023 · cited 6× · PMID 37224576 · DOI 10.1016/j.pediatrneurol.2023.04.019
Postneonatal epilepsy after acute provoked neonatal seizures: Incidence, predictors, and clinical burden in a multicenter cohort followed through early childhood.
Numis AL, Glass HC, Soul JS, Wusthoff CJ, et al · · 2025 · cited 5× · PMID 40770895 · DOI 10.1111/epi.18590
Impact of COVID-19 Pandemic on Developmental Service Delivery in Children With a History of Neonatal Seizures.
Peyton C, Girvan O, Shellhaas RA, Lemmon ME, et al · · 2022 · cited 5× · PMID 35149302 · DOI 10.1016/j.pediatrneurol.2022.01.004
Parent and Family Well-Being and Associated Risk Factors as Children with Neonatal Seizures Reach Preschool and School-Age: A Longitudinal Cohort Study.
Franck LS, Lemmon ME, Grossbauer L, Pawlowski K, et al · · 2025 · cited 1× · PMID 40510235 · DOI 10.1016/j.jpedcp.2025.200149
Sleep Disorders Five Years After Acute Provoked Neonatal Seizures.
Shellhaas RA, Franck LS, Pilon B, Wusthoff CJ, et al · · 2025 · cited 1× · PMID 39557387 · DOI 10.1016/j.jpeds.2024.114412

Verify or expand the search:

Other recruiting trials for Neonatal Seizure

Currently open trials in the same condition.

NCT05610085 — A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures · Phase 2 · recruiting
NCT05361070 — Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy · active not recruiting
NCT04831242 — Monitoring Key Activity and Physiology of Neonates in Intensive Care · recruiting

Other University of California, San Francisco trials

Trials by the same sponsor.

NCT05284773 — Screening for Acute Malnutrition · NA · withdrawn
NCT04634851 — Video Home Visits for Dietary Counselling · NA · not yet recruiting
NCT06065670 — Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a M · Phase 1, PHASE2 · not yet recruiting
NCT07534098 — Intervention for Hearing Health Among Native Americans · NA · not yet recruiting
NCT06960421 — Exercise-based Frailty Intervention in Lung Transplantation (XFIT) · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04337697 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
Last refreshed: 5 February 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04337697.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing