Last reviewed · How we verify
NCT05361070: NSR-GENE
Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy
trial in Neonatal Seizure in 300 participants. Participants enrolled and being followed up; not accepting new ones.
28 February 2027
Quick facts
| Lead sponsor | University of California, San Francisco |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 300 |
| Start date | 9 August 2022 |
| Primary completion | 28 February 2027 |
| Estimated completion | 28 February 2027 |
| Sites | 8 locations across United States |
Conditions studied
- Neonatal Seizure — all drugs for Neonatal Seizure →
- Hypoxic-Ischemic Encephalopathy — all drugs for Hypoxic-Ischemic Encephalopathy →
- Stroke — all drugs for Stroke →
- Intracranial Hemorrhage — all drugs for Intracranial Hemorrhage →
Sponsor
University of California, San Francisco
Who can join
Eligibility, any sex, with Neonatal Seizure or Hypoxic-Ischemic Encephalopathy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The NSR-GENE study is a longitudinal cohort study of approximately 300 parent-child trios from the Neonatal Seizure Registry and participating site outpatient clinics that aims to evaluate whether and how genes alter the risk of post-neonatal epilepsy among children with acute provoked neonatal seizures. The researchers aim to develop prediction rules to stratify neonates into low, medium, and high risk for post-neonatal epilepsy based on clinical, electroencephalogram (EEG), magnetic resonance imaging (MRI), and genetic risk factors.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Updates on the diagnostic evaluation, genotype-phenotype correlation, and treatments of genetic epilepsies.
Zimmern V, Korff C. · · 2022 · cited 1× · PMID 36081356 · DOI 10.1097/mop.0000000000001170
Verify or expand the search:
- PubMed search for NCT05361070
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Neonatal Seizure
Currently open trials in the same condition.
- NCT05610085 — A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures · Phase 2 · recruiting
- NCT04831242 — Monitoring Key Activity and Physiology of Neonates in Intensive Care · recruiting
Other University of California, San Francisco trials
Trials by the same sponsor.
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- NCT06065670 — Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a M · Phase 1, PHASE2 · not yet recruiting
- NCT07534098 — Intervention for Hearing Health Among Native Americans · NA · not yet recruiting
- NCT06960421 — Exercise-based Frailty Intervention in Lung Transplantation (XFIT) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05361070 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
- Last refreshed: 5 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05361070.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing