Last reviewed · How we verify

NCT04202926

Repetitive dTMS Intervention for Methamphetamine Addiction

Completed NA Last updated 22 November 2023
What this trial tests

NA trial testing real coil in Methamphetamine-dependence in 23 participants. Completed in 30 October 2023.

Timeline
30 December 2019
Primary endpoint
30 May 2023
30 October 2023

Quick facts

Lead sponsorShanghai Mental Health Center
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposetreatment
Enrollment23
Start date30 December 2019
Primary completion30 May 2023
Estimated completion30 October 2023
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Shanghai Mental Health Center — full company profile →

Who can join

Adults 18 to 60, any sex, with Methamphetamine-dependence. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A growing body of evidence suggests a wide range of brain areas including medial prefrontal cortex (mPFC), dorsolateral prefrontal cortex (DLPFC) and other subcortical regions, such as anterior cingulate cortex (ACC) are critical for regulating cognitive control over decisions and involving in drug related cue processing. Previous studies have demonstrated that transcranial magnetic stimulation (rTMS) over dorsolateral prefrontal cortex reduces craving for meth dependences. Specifically, the H7 coil induces a magnetic field can target mPFC and ACC. In this study, the investigators investigated whether repeated dTMS intervention of medial prefrontal and cingulate cortices in methamphetamine addiction could reduce the subjective craving and improve the cognitive abilities.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Deep magnetic stimulation targeting the medial prefrontal and anterior cingulate cortices for methamphetamine use disorder: a randomised, double-blind, sham-controlled study.
    Zhao D, Zeng N, Zhang HB, Zhang Y, et al · · 2023 · cited 6× · PMID 37781340 · DOI 10.1136/gpsych-2023-101149

Verify or expand the search:

Other recruiting trials for Methamphetamine-dependence

Currently open trials in the same condition.

Other Shanghai Mental Health Center trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04202926.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing