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NCT05162391: IMSTI
Inflammation in Methamphetamine and STIs (IMSTI)
NA trial testing Contingency Management in Methamphetamine-dependence in 30 participants. Participants enrolled and being followed up; not accepting new ones.
30 June 2026
Quick facts
| Lead sponsor | University of California, Los Angeles |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 30 |
| Start date | 31 May 2022 |
| Primary completion | 30 June 2026 |
| Estimated completion | 30 June 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Contingency Management
Conditions studied
- Methamphetamine-dependence — all drugs for Methamphetamine-dependence →
- Rectal Gonorrhea — all drugs for Rectal Gonorrhea →
- Rectal Chlamydia — all drugs for Rectal Chlamydia →
Sponsor
University of California, Los Angeles
Who can join
18 and older, male only, with Methamphetamine-dependence or Rectal Gonorrhea. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial aims to investigate the effects of a decline in methamphetamine use on rectal inflammatory cytokine levels, substance use contexts, and HIV/STI risk behavior. This clinical trial also seeks to evaluate joint effects of methamphetamine use and rectal gonorrhea/chlamydia infection on rectal inflammatory cytokine levels. The proposed trial will consist of 40 MSM, half with rectal gonorrhea/chlamydia infection at enrollment (n=20), with methamphetamine use disorder that will receive contingency management for methamphetamine reduction. Following baseline measurement, participants will be observed over the course of 8 weeks, where participants will complete behavioral surveys, provide urine for drug testing, and rectal samples for measurement of rectal inflammatory cytokine levels.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05162391
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other recruiting trials for Methamphetamine-dependence
Currently open trials in the same condition.
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- NCT06233799 — Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder · Phase 3 · recruiting
- NCT06027814 — MHealth Incentivized Adherence Plus Patient Navigation · NA · active not recruiting
- NCT06434818 — Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders · Phase 2 · recruiting
- NCT03470480 — rTMS for Craving in Methamphetamine Use Disorder · NA · recruiting
Other University of California, Los Angeles trials
Trials by the same sponsor.
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- NCT04996667 — Effect of iNO in Patients With Submassive and Massive PE · Phase 2 · withdrawn
- NCT05067387 — Evaluation of Oral THC and CBD in Men and Women · Phase 1 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05162391 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, Los Angeles
- Last refreshed: 15 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05162391.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing