NCT04178018

Transvaginal Ultrasound and Photoacoustic Imaging of Ovary

Recruiting now NA Last updated 28 November 2025

What this trial tests

NA trial testing Photoacoustic imaging in Ovary; Anomaly in 310 participants. Currently enrolling.

Timeline

9 February 2020

Primary endpoint
31 January 2027

31 January 2027

Quick facts

Lead sponsor	Washington University School of Medicine
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	310
Start date	9 February 2020
Primary completion	31 January 2027
Estimated completion	31 January 2027
Sites	1 location across United States

Drugs / interventions tested

• Photoacoustic imaging
• Ultrasound

Conditions studied

• Ovary; Anomaly — all drugs for Ovary; Anomaly →

Sponsor

Washington University School of Medicine

Who can join

18 and older, female only, with Ovary; Anomaly. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is being conducted to validate if photoacoustic imaging potentially reduces benign surgeries without compromising cancer detection sensitivity. The study will also explore whether using the photoacoustic imaging/ultrasound technique has any potential with early ovarian cancer detection in a group of high risk patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Characterization of adnexal lesions using photoacoustic imaging to improve sonographic O-RADS risk assessment.
   Zhu Q, Luo H, Middleton WD, Itani M, et al · · 2023 · cited 3× · PMID 37606287 · DOI 10.1002/uog.27452