NCT03937661 (PRP) is a Phase 2, PHASE3 clinical trial of PRP in Ovary; Anomaly, sponsored by Genesis Athens Clinic.

Who is sponsoring NCT03937661?

NCT03937661 is sponsored by Genesis Athens Clinic.

What drugs are being tested in NCT03937661?

Interventions in NCT03937661: PRP, Placebo.

What condition does NCT03937661 study?

NCT03937661 studies Ovary; Anomaly, Infertility, Female.

Is NCT03937661 still recruiting?

NCT03937661 is currently recruiting now. Last updated 27 December 2024.

Last reviewed 2024-12-27 · How we verify

NCT03937661: PRP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Autologous Platelet-Rich Plasma Intra-ovarian Infusion in Poor Responders

Recruiting now Phase 2, PHASE3 Last updated 27 December 2024

What this trial tests

Phase 2, PHASE3 trial testing PRP in Ovary; Anomaly in 100 participants. Currently enrolling.

Timeline

6 May 2019

Primary endpoint
30 January 2025

30 August 2025

Quick facts

Lead sponsor	Genesis Athens Clinic
Phase	Phase 2, PHASE3
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	100
Start date	6 May 2019
Primary completion	30 January 2025
Estimated completion	30 August 2025
Sites	1 location across Greece

Drugs / interventions tested

PRP — full drug profile →
Placebo

Conditions studied

Ovary; Anomaly — all drugs for Ovary; Anomaly →
Infertility, Female — all drugs for Infertility, Female →

Sponsor

Genesis Athens Clinic

Who can join

Adults 35 to 47, female only, with Ovary; Anomaly or Infertility, Female. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Autologous PRP intra ovarian infusion may improve ovarian response, patients' hormonal profile as well as fresh embryo transfer (ET)-ICSI cycles' outcome in patients presenting with Poor Ovarian Response (POR).

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Reactivating Ovarian Function through Autologous Platelet-Rich Plasma Intraovarian Infusion: Pilot Data on Premature Ovarian Insufficiency, Perimenopausal, Menopausal, and Poor Responder Women.
Sfakianoudis K, Simopoulou M, Grigoriadis S, Pantou A, et al · · 2020 · cited 76× · PMID 32532000 · DOI 10.3390/jcm9061809
Autologous platelet-rich plasma for assisted reproduction.
Vaidakis D, Papapanou M, Siristatidis CS. · · 2024 · cited 20× · PMID 38682756 · DOI 10.1002/14651858.cd013875.pub2
Therapeutic roles of platelet-rich plasma to restore female reproductive and endocrine dysfunction.
Wang X, Li J, Lu W, Gao F, et al · · 2024 · cited 8× · PMID 38654928 · DOI 10.3389/fendo.2024.1374382
Research trends on platelet-rich plasma in improving ovarian dysfunction: A bibliometric and visualization analysis.
Liu F, Li J, Li J, Lan M, et al · · 2025 · PMID 41079455 · DOI 10.1016/j.reth.2025.09.010

Verify or expand the search:

Other trials of PRP

Trials testing the same drug.

NCT07453953 — A Comparison of Clinical Efficacy of Mytocel MSK With AMT and PRP Injections in Patients With Knee Osteoarthritis · EARLY_PHASE1 · not yet recruiting
NCT07565844 — Intradermal Exosomes, Platelet-Rich Plasma, and Steroids for Post-Herpetic Neuralgia · NA · recruiting
NCT06384859 — Effectiveness of Extracorporeal Shockwave Therapy Combined With Platelet-rich Plasma in the Treatment of Chronic Inserti · Phase 4 · not yet recruiting
NCT06339645 — Intravesical Platelet-rich Plasma Injection in Patients With Interstitial Cystitis/Bladder-A Retrospective Study · unknown
NCT06332352 — Intra-articular Platelet-Rich Plasma for Acetabular Labral Tears · NA · completed

Other recruiting trials for Ovary; Anomaly

Currently open trials in the same condition.

NCT04178018 — Transvaginal Ultrasound and Photoacoustic Imaging of Ovary · NA · recruiting
NCT05181748 — Autologous Platelet Rich Plasma Intraovarian Infusion for Poor Responders · Phase 2, PHASE3 · recruiting

Other Genesis Athens Clinic trials

Trials by the same sponsor.

NCT05205993 — Εffectiveness of Intrauterine Antibiotic Administration for Treatment of Chronic Endometritis · Phase 2 · unknown
NCT04031456 — Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients · Phase 2, PHASE3 · recruiting
NCT03951194 — Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women · Phase 2, PHASE3 · unknown
NCT03916978 — Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women · Phase 2, PHASE3 · recruiting
NCT05181748 — Autologous Platelet Rich Plasma Intraovarian Infusion for Poor Responders · Phase 2, PHASE3 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03937661 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Genesis Athens Clinic
Last refreshed: 27 December 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03937661.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing