Who is sponsoring NCT04149028?

NCT04149028 is sponsored by Tanta University.

What drugs are being tested in NCT04149028?

Interventions in NCT04149028: PRP injection inside the ovary by laparoscoy. The injection volume is 2 ml.

What condition does NCT04149028 study?

NCT04149028 studies Premature Ovarian Failure.

Is NCT04149028 still recruiting?

NCT04149028 is currently completed. Last updated 17 February 2023.

Last reviewed 2023-02-17 · How we verify

NCT04149028

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Platelet Rich Plasma Injection Into Ovary of Patients With Premature Ovarian Insufficiency

Completed NA Last updated 17 February 2023

What this trial tests

NA trial testing PRP injection inside the ovary by laparoscoy. The injection volume is 2 ml in Premature Ovarian Failure in 16 participants. Completed in 31 December 2022.

Timeline

1 December 2019

Primary endpoint
31 December 2022

31 December 2022

Quick facts

Lead sponsor	Tanta University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	16
Start date	1 December 2019
Primary completion	31 December 2022
Estimated completion	31 December 2022
Sites	1 location across Egypt

Drugs / interventions tested

PRP injection inside the ovary by laparoscoy. The injection volume is 2 ml

Conditions studied

Premature Ovarian Failure — all drugs for Premature Ovarian Failure →

Sponsor

Tanta University

Who can join

Adults 18 to 35, female only, with Premature Ovarian Failure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

All encountered cases with POI will be assessed and examined then investigated. Eligible cases will be included in the study

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Therapeutic roles of platelet-rich plasma to restore female reproductive and endocrine dysfunction.
Wang X, Li J, Lu W, Gao F, et al · · 2024 · cited 8× · PMID 38654928 · DOI 10.3389/fendo.2024.1374382
Platelet-Rich Plasma (PRP) in Reproductive Medicine: A Critical Review of PRP Therapy in Low-Reserve and Premature Ovarian Insufficiency.
Moustakli E, Potiris A, Zikopoulos A, Zachariou A, et al · · 2025 · cited 2× · PMID 40427083 · DOI 10.3390/biomedicines13051257
Research trends on platelet-rich plasma in improving ovarian dysfunction: A bibliometric and visualization analysis.
Liu F, Li J, Li J, Lan M, et al · · 2025 · PMID 41079455 · DOI 10.1016/j.reth.2025.09.010

Verify or expand the search:

Other recruiting trials for Premature Ovarian Failure

Currently open trials in the same condition.

NCT05740579 — The Danish TURNER Cryopreservation Study · NA · recruiting
NCT05462379 — Autologous Heterotopic Fresh Ovarian Graft in Woman With LACC Eligible for Pelvic Radiotherapy Treatment. · Phase 1, PHASE2 · active not recruiting
NCT04815213 — The Use of Expandeded Mesenchymal Stromal Cells (MSC) in Premature Ovarian Failure (POF) in Adult Humans · Phase 1 · active not recruiting
NCT04390308 — Is There A Role For Mechanical Stimulation In Ovarian Follicular Activation? · recruiting
NCT04381299 — Will Autologous Platelet Rich Plasma Able To Restore Ovarian Function? · active not recruiting

Other Tanta University trials

Trials by the same sponsor.

NCT07398651 — Apremilast and Adalimumab in Psoriatic Arthritis Patients · NA · not yet recruiting
NCT06966856 — This Randomized, Clinical Trial Evaluates the Efficacy of Oral Versus Sublingual Vitamin B12 Supplementation in Correcti · Phase 3 · not yet recruiting
NCT07334197 — Effect of Melatonin on Left Ventricular Reverse Remodeling and Inflammation in Peripartum Cardiomyopathy · NA · not yet recruiting
NCT07498998 — Glucocorticoid, Ozone and 5% Dextrose Local Injection for Pain Relief in Carpal Tunnel Syndrome · NA · not yet recruiting
NCT07114250 — Comparative Study Between Spinal Anesthesia Versus General Anesthesia in Supine Percutaneous Nephrolithotomy Operation · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04149028 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Tanta University
Last refreshed: 17 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04149028.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing