NCT04051385

Assesment of Gingival Crevicular Fluid and Serum ErbB4/Neuregulin-4 Levels in Periodontal Disease and Health

Completed NA Last updated 9 August 2019

What this trial tests

NA trial testing non surgical periodontal treatment in Periodontitis in 80 participants. Completed in 18 January 2019.

Timeline

2 April 2018

Primary endpoint
18 January 2019

18 January 2019

Quick facts

Lead sponsor	Abant Izzet Baysal University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	diagnostic
Enrollment	80
Start date	2 April 2018
Primary completion	18 January 2019
Estimated completion	18 January 2019
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• non surgical periodontal treatment
• Gingival crevicular fluid and serum collection

Conditions studied

• Periodontitis — all drugs for Periodontitis →

Sponsor

Abant Izzet Baysal University

Who can join

18 and older, any sex, with Periodontitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aimed to investigate gingival crevicular fluid (GCF) and serum ErbB4 and Nrg4 levels in periodontal health and disease. A total of 80 individuals, 20 patients with stage II grade B periodontitis, 20 patients with stage III grade B periodontitis, 20 with gingivitis and 20 periodontally healthy individuals were included. Whole-mouth and site-specific clinical periodontal parameters including probing depth, clinical attachment level, bleeding on probing, gingival index, plaque index and papillar bleeding index were recorded. GCF and serum ErbB4 and Nrg4 levels were measured by enzyme-linked immunosorbent assay. Statistical analysis was performed by using non-parametric tests.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.