NCT03919006

Netrin 1 and Its Receptor Unc5b as Markers of Periodontal Disease

Completed NA Last updated 18 April 2019

What this trial tests

NA trial testing non surgical periodontal treatment in Periodontitis in 60 participants. Completed in 1 April 2019.

Timeline

1 January 2018

Primary endpoint
1 February 2019

1 April 2019

Quick facts

Lead sponsor	Abant Izzet Baysal University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	single
Primary purpose	diagnostic
Enrollment	60
Start date	1 January 2018
Primary completion	1 February 2019
Estimated completion	1 April 2019
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• non surgical periodontal treatment
• Gingival crevicular fluid, saliva and serum collection

Conditions studied

• Periodontitis — all drugs for Periodontitis →

Sponsor

Abant Izzet Baysal University

Who can join

18 and older, any sex, with Periodontitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aimed to investigate gingival crevicular fluid (GCF), saliva and serum Netrin 1 and Unc5b levels in periodontal health and disease. A total of 60 individuals, 20 patients with periodontitis, 20 with gingivitis and 20 periodontally healthy individuals were included. Whole-mouth and site-specific clinical periodontal parameters including probing depth, clinical attachment level, bleeding on probing, gingival index, plaque index and papillar bleeding index were recorded. GCF, salivary and serum Netrin 1 and Unc5b levels were measured by enzyme-linked immunosorbent assay. Statistical analysis was performed by using non-parametric tests.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.