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NCT04036981
Muscle Selection for Botulinum Toxin A Injection in Poststroke Elbow Flexor Spasticity
trial testing Botulinum toxin type A in Muscle Spasticity in 55 participants. Completed in 1 June 2021.
3 May 2021
Quick facts
| Lead sponsor | Izmir Katip Celebi University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 55 |
| Start date | 10 May 2019 |
| Primary completion | 3 May 2021 |
| Estimated completion | 1 June 2021 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Botulinum toxin type A (BOTULINUM TOXIN TYPE A) — full drug profile →
Conditions studied
- Muscle Spasticity — all drugs for Muscle Spasticity →
Sponsor
Izmir Katip Celebi University
Who can join
18 and older, any sex, with Muscle Spasticity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Botulinum toxin A (BoNT A) has been reported to be effective in the treatment of elbow flexor spasticity. Although BoNT A is an efficacious treatment option, there is a debate in the selection of target muscle(s) for BoNT injection in the treatment of poststroke elbow flexor spasticity. The decision of muscle selection for BoNT A injection is mostly made according to the physical examination findings in real life practice.One of the guiding findings in this decision is the position of the spastic arm. In this study, hypothesis is that the change in severity of spasticity with BoNT A injection differs depending on the muscle selection in chronic stroke patients with elbow flexor and forearm pronator spasticity.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of muscle selection for botulinum neurotoxin treatment on spasticity in patients with post-stroke elbow flexor muscle over-activity: an observational prospective study.
Şengül İ, Aşkın A, Tosun A. · · 2022 · cited 2× · PMID 34632927 · DOI 10.1080/08990220.2021.1986383
Verify or expand the search:
- PubMed search for NCT04036981
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other recruiting trials for Muscle Spasticity
Currently open trials in the same condition.
- NCT07118228 — Ultrasonographic Assessment of Muscle Morphology, Function, and Clinical Findings in Spastic Cerebral Palsy · recruiting
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- NCT06902168 — Effect of Diving and Aquatic Exercises on Muscle Spasticity and Motor Function in Children With Spastic Cerebral Palsy · NA · recruiting
- NCT06733025 — Comparing Upper Limb Surgery and Botulinum Toxin for Spasticity: A Paired Design Study · NA · recruiting
- NCT06536751 — Therapeutic Photobiomodulation and Tretament of Spasticity · Phase 2, PHASE3 · recruiting
Other Izmir Katip Celebi University trials
Trials by the same sponsor.
- NCT07460479 — Pilot Study of an Extended CBT Group Intervention for Intolerance of Uncertainty · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04036981 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Izmir Katip Celebi University
- Last refreshed: 23 June 2021
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