NCT06296082 (STROKEPOC) is a Phase 2, PHASE3 clinical trial of Botulinum toxin type A in Stroke, sponsored by Universiteit Antwerpen.

Who is sponsoring NCT06296082?

NCT06296082 is sponsored by Universiteit Antwerpen.

What drugs are being tested in NCT06296082?

Interventions in NCT06296082: Botulinum toxin type A, Dry Needling.

Is NCT06296082 still recruiting?

NCT06296082 is currently recruiting now. Last updated 20 February 2025.

Last reviewed 2025-02-20 · How we verify

NCT06296082: STROKEPOC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparative Study of the Effects of Dry Needling and Botulinum Toxin Type A as a Treatment for Lower Limb Post-stroke Spasticity

Recruiting now Phase 2, PHASE3 Last updated 20 February 2025

What this trial tests

Phase 2, PHASE3 trial testing Botulinum toxin type A in Stroke in 90 participants. Currently enrolling.

Timeline

1 September 2024

Primary endpoint
30 December 2025

31 December 2025

Quick facts

Lead sponsor	Universiteit Antwerpen
Phase	Phase 2, PHASE3
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	90
Start date	1 September 2024
Primary completion	30 December 2025
Estimated completion	31 December 2025
Sites	3 locations across Belgium, Canada, Spain

Drugs / interventions tested

Botulinum toxin type A (BOTULINUM TOXIN TYPE A) — full drug profile →
Dry Needling

Conditions studied

Stroke — all drugs for Stroke →

Sponsor

Universiteit Antwerpen — full company profile →

Who can join

Adults 18 to 75, any sex, with Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a randomized parallel group clinical trial which will be conducted in three countries (Spain, Canada and Belgium) comparing Botulinum Toxin type A (BTX-A) and Dry Needling (DN) effectiveness for post-stroke spasticity in participants who had a first stroke in the previous 12 months and have plantar flexor spasticity. Participants will be randomly allocated to receive either one session of BTX-A or 12 weekly sessions of DN. Blinded evaluators will assess the effects before, during, and after treatment, and at a 4-week follow-up.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Spinal mechanisms and feasibility of Dry Needling versus Botulinum Toxin Type A in post-stroke lower limb spasticity: A proof-of-concept randomized clinical trial protocol (STROKE-POC).
Pujol-Fuentes C, Eeckhaut B, Fernández Carnero S, Fernández Sanchís D, et al · · 2026 · PMID 42160369 · DOI 10.1371/journal.pone.0334571

Verify or expand the search:

Other trials of Botulinum toxin type A

Trials testing the same drug.

NCT07236632 — Hyaluronic Acid vs Botulinum Toxin Injection in Treatment of Lifelong Drug-Resistant Premature Ejaculation: Randomized S · NA · not yet recruiting
NCT06448676 — Head-to-Head Comparison of All Botulinum Neurotoxin Type A Products for Glabellar Rhytides · Phase 4 · not yet recruiting
NCT06385171 — Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation · recruiting
NCT06465056 — Use of Botulinum Toxin A in Direct Eyebrow Lift Scar · Phase 2 · recruiting
NCT06047444 — A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults · Phase 3 · active not recruiting

Other recruiting trials for Stroke

Currently open trials in the same condition.

NCT06615973 — Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke · recruiting
NCT07494890 — Measurement Properties of Mechanical Cost of Walking for Individuals With Walking Impairment · NA · recruiting
NCT07356011 — Exoskeleton for Balance · NA · recruiting
NCT07523503 — Unilateral Versus Bilateral Task-specific Training on Motor Impairment, Upper Extremity Function, and Hand Dexterity in · NA · recruiting
NCT06704074 — Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients · NA · recruiting

Other Universiteit Antwerpen trials

Trials by the same sponsor.

NCT07407569 — Developing a First-void Urine-based Infection Model to Study HPV-specific Antibody-virion Interaction Before and After H · Phase 2 · recruiting
NCT07355101 — Personalized Exercise Coaching to Improve Quality of Life in Pediatric IBD · NA · active not recruiting
NCT06962579 — The Effect of Personalized Exercise Interventions for the Prevention of Chemotherapy-induced Peripheral Neuropathy · NA · recruiting
NCT06999473 — Assessment and Treat Neglect Patients With a VR Application · NA · not yet recruiting
NCT07161531 — Test-retest Reliability of sEMG to Measure Fatigue in Adolescents · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06296082 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universiteit Antwerpen
Last refreshed: 20 February 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06296082.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing