NCT03983720 (FatSEP) is a Phase 2 clinical trial of Evaluation of degree chronic fatigue. in Sclerosis, Multiple, sponsored by Centre Hospitalier Universitaire de Saint Etienne.

Who is sponsoring NCT03983720?

NCT03983720 is sponsored by Centre Hospitalier Universitaire de Saint Etienne.

What drugs are being tested in NCT03983720?

Interventions in NCT03983720: Evaluation of degree chronic fatigue., Questionnaires, Blood sample, Cardiopulmonary evaluation, Capacity of muscular oxygen extraction, Sleep assessment, Metabolic fatigue, Neuromuscular evaluation.

What condition does NCT03983720 study?

NCT03983720 studies Sclerosis, Multiple.

Is NCT03983720 still recruiting?

NCT03983720 is currently terminated. Last updated 2 November 2023.

Last reviewed 2023-11-02 · How we verify

NCT03983720: FatSEP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Can Fatigability Neuromuscular Explain Chronic Fatigue in People With Multiple Sclerosis?

Terminated Phase 2 Last updated 2 November 2023

What this trial tests

Phase 2 trial testing Evaluation of degree chronic fatigue. in Sclerosis, Multiple in 67 participants. Terminated before completion.

Timeline

21 January 2020

Primary endpoint
16 June 2021

31 July 2021

Quick facts

Lead sponsor	Centre Hospitalier Universitaire de Saint Etienne
Phase	Phase 2
Status	Terminated
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	single
Primary purpose	diagnostic
Enrollment	67
Start date	21 January 2020
Primary completion	16 June 2021
Estimated completion	31 July 2021
Sites	1 location across France

Drugs / interventions tested

Evaluation of degree chronic fatigue.
Questionnaires
Blood sample — full drug profile →
Cardiopulmonary evaluation
Capacity of muscular oxygen extraction
Sleep assessment
Metabolic fatigue
Neuromuscular evaluation

Conditions studied

Sclerosis, Multiple — all drugs for Sclerosis, Multiple →

Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Who can join

Adults 18 to 70, any sex, with Sclerosis, Multiple. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Chronic fatigue is the most common and debilitating symptom in multiple sclerosis patients. This chronic fatigue affects their quality of life by decreasing their capacity to perform simple tasks of daily life. The aim of the present project is to determine whether deteriorated neuromuscular function (i.e. increased fatigability) is involved in this feeling of chronic fatigue. Because the causes of this feeling are multi-dimensional, a large battery of tests will allow us to better understand the origin of chronic fatigue. A better knowledge of chronic fatigue etiology will allow to optimize rehabilitation treatments to decrease the apparition/persistence of chronic fatigue and in fine improve quality of life.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Sclerosis, Multiple

Currently open trials in the same condition.

NCT06112639 — The DANCEREX Proof-of-Concept Study for Chronic Neurological Disorders · NA · recruiting
NCT06428201 — The Efficacy of Tele Rehabilitation- Based Task-Specific Training for Cognitive Function Improvement · NA · active not recruiting
NCT05857280 — EXOPULSE Mollii Suit, Motor Function & Multiple Sclerosis (EXOSEP 2) · NA · recruiting
NCT03900221 — French Registry for Monitoring Pregnancies for Multiple Sclerosis · recruiting
NCT03600779 — Application of ihMT MRI in Multiple Sclerosis · NA · recruiting

Other Centre Hospitalier Universitaire de Saint Etienne trials

Trials by the same sponsor.

NCT07326579 — Effects of a Sleep Education Program on the Health Status of Healthcare Workers Working 12-hour Alternating Day-night Sh · NA · not yet recruiting
NCT07504003 — Influence of Training Session Duration on Improvements in Physiological Resilience to Exercise · NA · recruiting
NCT07483710 — Association Between Muscle L3 CT Scan Muscle Derived Parameters of Muscle Function Upon Intensive Care Unit Admission an · NA · not yet recruiting
NCT06845176 — Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery · NA · recruiting
NCT07344298 — Less is Better? Effectiveness of a Short Local Vibration Protocol on Neuromuscular Function · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03983720 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Saint Etienne
Last refreshed: 2 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03983720.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing