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NCT07344298: VIB-EXPRESS

Less is Better? Effectiveness of a Short Local Vibration Protocol on Neuromuscular Function

Recruiting now NA Last updated 27 March 2026
What this trial tests

NA trial testing Local vibration protocol in Healthy Volonteers in 72 participants. Currently enrolling.

Timeline
23 March 2026
Primary endpoint
22 January 2028
22 January 2028

Quick facts

Lead sponsorCentre Hospitalier Universitaire de Saint Etienne
PhaseNA
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposeother
Enrollment72
Start date23 March 2026
Primary completion22 January 2028
Estimated completion22 January 2028
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Who can join

Adults 18 to 45, any sex, with Healthy Volonteers. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Local vibration is a non-invasive neuromuscular stimulation modality used in training and rehabilitation for its effects on neuromuscular function, particularly its ability to induce nervous adaptations. Its passive application is particularly useful in cases of motor deficit or immobilization. Several studies, including our own, have shown that vibration protocols over several weeks can induce significant gains in muscle strength, particularly in the knee extensors. However, the parameters of application remain heterogeneous, particularly with regard to the duration of the interventions. With this in mind, a prospective controlled study is being conducted in healthy subjects, comparing four modalities of local vibration intervention targeting the knee extensors: an intensive vibration protocol over 5 consecutive days (1 session of 30 or 60 minutes per day) and a protocol spread over 4 weeks at a rate of 3 weekly sessions of 30 or 60 minutes). The objective is to evaluate and compare their immediate and delayed effects on force production and corticospinal properties. The results of this study will thus help optimize recommendations regarding the use of local vibration in muscle strengthening and neuromuscular reconditioning strategies.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other Centre Hospitalier Universitaire de Saint Etienne trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07344298.

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