Last reviewed · How we verify
NCT03970148
YAG Laser Vitreolysis for Floaters
NA trial testing Nd: YAG laser in Vitreous Detachment in 100 participants. Status unknown.
2 October 2019
Quick facts
| Lead sponsor | University Hospital of Split |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 2 April 2019 |
| Primary completion | 2 October 2019 |
| Estimated completion | 30 December 2020 |
| Sites | 1 location across Croatia |
Drugs / interventions tested
- Nd: YAG laser
Conditions studied
- Vitreous Detachment — all drugs for Vitreous Detachment →
Sponsor
University Hospital of Split
Who can join
18 and older, any sex, with Vitreous Detachment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Vitreous fluid, containing 95% water, fills the space behind the lens. Its gelatinous consistency is due to the presence of hyaluronic acid, mucopolysaccharide and collagen fibers. With age, the collagen aggregates into parallel bundles, bound by cross links, leaving the pockets of liquid in the glass body. This redistribution is referred to as syneresis, which is found in 90% older than 40 years. After liquefaction, the vitreous enters the retroviral space and separates the posterior hyaloid membrane from the retina. When separating from the optical disk it forms an annular formation (Weiss ring) in front of the optical disc. These agglomerated collagen bundles (opacities) disperse the photons of light and are perceived by the patients as a "gray silhouette-like artifact". Two major interventions for these symptoms include Nd: YAG laser vitreolysis and vitrectomy. The less invasive method Nd: YAG laser increases the temperature of the opacity thus vaporizing them to smaller fragments that are easier to sediment onto the bottom of the vitreous cavity thereby relieving the symptoms.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03970148
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other University Hospital of Split trials
Trials by the same sponsor.
- NCT07130006 — Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures · Phase 4 · not yet recruiting
- NCT06595329 — Comparison Between Epidural Analgesia and Intrathecal Opioid Analgesia for Pain Management in Open Nephrectomy · Phase 1 · recruiting
- NCT06399445 — Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizin · Phase 4 · recruiting
- NCT06051825 — Diagnostic Importance of the C-reactive Protein From Blood and Saliva in Children With Acute Appendicitis · unknown
- NCT05537272 — The Efficacy of Tamsulosin and Tadalafil Compared to Placebo in the Treatment and Prevention of Urinary Disorders After · Phase 4 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03970148 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital of Split
- Last refreshed: 11 June 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03970148.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing