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NCT03964376: POSAII
Nasal High Flow Therapy in Surgical Patients with Unrecognized Obstructive Sleep Apnea
NA trial testing Nasal High Flow in Obstructive Sleep Apnea in 22 participants. Completed in 8 January 2025.
8 January 2025
Quick facts
| Lead sponsor | University Health Network, Toronto |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 22 |
| Start date | 1 October 2019 |
| Primary completion | 8 January 2025 |
| Estimated completion | 8 January 2025 |
| Sites | 8 locations across Hong Kong, Singapore, Canada, Malaysia |
Drugs / interventions tested
- Nasal High Flow
- Usual Care
Conditions studied
- Obstructive Sleep Apnea — all drugs for Obstructive Sleep Apnea →
- Sleep Disordered Breathing — all drugs for Sleep Disordered Breathing →
Sponsor
University Health Network, Toronto
Who can join
45 and older, any sex, with Obstructive Sleep Apnea or Sleep Disordered Breathing. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this study the investigators will determine whether using high flow oxygen in moderate-to-severe Obstructive Sleep Apnea patients following a major non cardiac surgery is more efficacious than usual care in preventing decrease in oxygen level in blood.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03964376
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Nasal High Flow
Trials testing the same drug.
- NCT05167201 — Domiciliary Nasal High Flow and Patient Outcomes in Chronic Hypercapnic Respiratory Failure in the United Kingdom · NA · unknown
- NCT03466385 — NHF vs NIV in Patients With Acute Exacerbation of COPD · NA · unknown
- NCT02230020 — Efficacy of High Flow Therapy in COPD At Home · terminated
Other recruiting trials for Obstructive Sleep Apnea
Currently open trials in the same condition.
- NCT07195253 — Oro-myofunctional Characteristics and Obstructive Sleep Apnea in Infants With Down Syndrome · recruiting
- NCT07273019 — Tongue Muscular Assessment in Children With Sleep Disordered Breathing · NA · recruiting
- NCT07447011 — Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea · NA · recruiting
- NCT07397780 — RPMO2 Oximeter Accuracy During Sleep 1 Trial · active not recruiting
- NCT06698809 — Obstructive Sleep Apnea Therapeutic Intervention for REsiDual Sleepiness · NA · recruiting
Other University Health Network, Toronto trials
Trials by the same sponsor.
- NCT06831032 — Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response · NA · recruiting
- NCT06634056 — Pneumonitis Prevention Protocol Using Pentoxifylline and α-tocopherol In Stage III Non-Small Cell Lung Cancer Patients U · Phase 2 · not yet recruiting
- NCT06836726 — Clinical Trial to Test Efficacy of Targeting Hypoxia Combined With ARSI After First-line ARSI Therapy for Castrate Resis · Phase 2 · not yet recruiting
- NCT07515651 — Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas · Phase 2 · not yet recruiting
- NCT07509450 — Fecal Microbiota Transplantation in Patients Undergoing Chimeric Antigen Receptor T-cell Therapy and Allogeneic Stem Cel · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03964376 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Health Network, Toronto
- Last refreshed: 13 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03964376.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing