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NCT06698809: STIL TIRED

Obstructive Sleep Apnea Therapeutic Intervention for REsiDual Sleepiness

Recruiting now NA Last updated 14 January 2026
What this trial tests

NA trial testing Active tPBM in Obstructive Sleep Apnea in 22 participants. Currently enrolling.

Timeline
12 January 2026
Primary endpoint
1 September 2026
3 October 2026

Quick facts

Lead sponsorNYU Langone Health
PhaseNA
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment22
Start date12 January 2026
Primary completion1 September 2026
Estimated completion3 October 2026
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

NYU Langone Health — full company profile →

Who can join

Adults 18 to 75, any sex, with Obstructive Sleep Apnea or Sleepiness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Obstructive sleep apnea (OSA) is a sleep disorder that is commonly treated using positive airway pressure, yet 50% of patients still experience residual sleepiness after successful therapy. A potential neuromodulation strategy that can decrease residual sleepiness is transcranial photobiomodulation (tPBM). tPBM is a neuromodulatory treatment that uses red and/or near infrared light to penetrate the cortex and can alter both cerebral metabolism and blood flow. However, this potential has never been explored before directly in sleep disordered individuals. This project aims to explore the effect of tPBM on sleepiness and understand the potential neural mechanism of tPBM in OSA. The short-term goal of this project is to collect pilot data, which is the first of its kind, and suggest tPBM as a potential modulator of sleepiness in OSA.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Obstructive Sleep Apnea

Currently open trials in the same condition.

Other NYU Langone Health trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06698809.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing