NCT03956264 (ARVACC) is a NA clinical trial of Virtual Reality in Surgery, Cardiac, sponsored by CMC Ambroise Paré.

Who is sponsoring NCT03956264?

NCT03956264 is sponsored by CMC Ambroise Paré.

What drugs are being tested in NCT03956264?

Interventions in NCT03956264: Virtual Reality, Kalinox.

What condition does NCT03956264 study?

NCT03956264 studies Surgery, Cardiac.

Is NCT03956264 still recruiting?

NCT03956264 is currently completed. Last updated 8 April 2026.

Last reviewed 2026-04-08 · How we verify

NCT03956264: ARVACC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Interest of Virtual Reality in the Management of Anxiety and Pain Related to Post-cardiac Surgery Care

Completed NA Last updated 8 April 2026

What this trial tests

NA trial testing Virtual Reality in Surgery, Cardiac in 200 participants. Completed in 24 July 2020.

Timeline

26 September 2019

Primary endpoint
24 July 2020

24 July 2020

Quick facts

Lead sponsor	CMC Ambroise Paré
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	200
Start date	26 September 2019
Primary completion	24 July 2020
Estimated completion	24 July 2020
Sites	1 location across France

Drugs / interventions tested

Virtual Reality
Kalinox — full drug profile →

Conditions studied

Surgery, Cardiac — all drugs for Surgery, Cardiac →

Sponsor

CMC Ambroise Paré — full company profile →

Who can join

18 and older, any sex, with Surgery, Cardiac. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study compares Virtual Reality versus Nitrous oxide administration for the management of anxiety and pain related to post-cardiac surgery care, especially during removal of mediastinal drainage.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Virtual reality vs. Kalinox® for management of pain in intensive care unit after cardiac surgery: a randomized study.
Laghlam D, Naudin C, Coroyer L, Aidan V, et al · · 2021 · cited 31× · PMID 33983498 · DOI 10.1186/s13613-021-00866-w
Using Virtual Reality to Improve Outcomes Related to Quality of Life Among Older Adults With Serious Illnesses: Systematic Review of Randomized Controlled Trials.
Maheta B, Kraft A, Interrante N, Fereydooni S, et al · · 2025 · cited 10× · PMID 40009834 · DOI 10.2196/54452

Verify or expand the search:

Other trials of Virtual Reality

Trials testing the same drug.

NCT07126548 — A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men · NA · not yet recruiting
NCT07512999 — The Effect of Using Nature Sounds and Virtual Reality During the Non-Stress Test · NA · not yet recruiting
NCT07520253 — Effect of Virtual Reality on Cortical Reorganization and Upper Extremity Functional Recovery in Patients With Subacute S · NA · not yet recruiting
NCT07462039 — Effect of Virtual Reality on Pain and Anxiety During Pap Smear Testing · NA · not yet recruiting
NCT07400874 — Use of Acupressure, Aromatherapy, and Virtual Reality for Children in During Blood Collection Procedures · NA · not yet recruiting

Other recruiting trials for Surgery, Cardiac

Currently open trials in the same condition.

NCT06109155 — The Effect of ACT and Tranexamic Acid on Bleeding in Cardiac Surgery · Phase 4 · recruiting
NCT06554925 — SEx-specific Differences in Cardiac Surgery Patients (SECS). · recruiting

Other CMC Ambroise Paré trials

Trials by the same sponsor.

NCT07477730 — Local Infiltration Analgesia Versus Quadruple Nerve Blocks in Total Knee Arthroplasty. · NA · not yet recruiting
NCT07345559 — Personalisation of Mean Arterial Pressure in Adult Patients With Cardiogenic Shock · NA · recruiting
NCT07332949 — Impact of Dialysis on Sexuality. · recruiting
NCT06777355 — Association Between Portal Flow Pulsatility and Right Ventricular Dysfunction in the Postoperative Period of Cardiac Sur · completed
NCT06327334 — Brain Heart InterActioNs in Cardiac Arrest. Ancillary Study of the HEAVENwARd Trial · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03956264 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by CMC Ambroise Paré
Last refreshed: 8 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03956264.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing