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NCT03926949: OPPortuNity
Outpatient Preoperative Parenteral Nutrition in Malnourished Surgical Patients
NA trial testing Parenteral Nutrition in Malnutrition in 60 participants. Currently enrolling.
31 July 2026
Quick facts
| Lead sponsor | University of Alberta |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 30 October 2019 |
| Primary completion | 31 July 2026 |
| Estimated completion | 31 July 2026 |
| Sites | 2 locations across Canada |
Drugs / interventions tested
- Parenteral Nutrition — full drug profile →
- Standard Nutrition Care
Conditions studied
- Malnutrition — all drugs for Malnutrition →
- Surgery — all drugs for Surgery →
Sponsor
University of Alberta
Who can join
18 and older, any sex, with Malnutrition or Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Malnutrition is common in surgical patients. Many studies have shown a clear association between malnutrition and poor surgical outcomes. Parenteral nutrition (PN) is a nutrition intervention that is given by vein and can be safely provided to malnourished patients. It contains carbohydrates, fats, and protein just like you would normally in your diet. Pre-operative PN is able to improve outcomes in surgical patients. However, pre-operative PN has traditionally required hospital admission which results in increased length of stay, hospital cost, and hospital-acquired infection. Moreover, in hospital pre-operative PN may not be feasible or prioritized when access to inpatient surgery beds is limited. Outpatient PN provides the opportunity to solve this problem. The feasibility and impact of outpatient PN in malnourished patients undergoing major surgery have not previously been studied. This study aims to evaluate the feasibility of outpatient pre-operative PN and its effect on patient's outcomes.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Role of Preoperative Parenteral Nutrition.
Lakananurak N, Gramlich L. · · 2020 · cited 26× · PMID 32384662 · DOI 10.3390/nu12051320
Verify or expand the search:
- PubMed search for NCT03926949
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Parenteral Nutrition
Trials testing the same drug.
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- NCT03115957 — Early Versus Delayed Parenteral Nutrition in Abdominal Surgical Patients · NA · completed
Other recruiting trials for Malnutrition
Currently open trials in the same condition.
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- NCT06687291 — Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer · recruiting
- NCT06837194 — Washed Microbiota Transplantation Combined With Enteral Nutrition for Gastroptosis · recruiting
Other University of Alberta trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03926949 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Alberta
- Last refreshed: 21 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03926949.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing