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NCT03115957: PNASIT
Early Versus Delayed Parenteral Nutrition in Abdominal Surgical Patients
NA trial testing Parenteral Nutrition in Digestive System Neoplasms in 230 participants. Completed in 22 February 2019.
30 December 2018
Quick facts
| Lead sponsor | Jinling Hospital, China |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 230 |
| Start date | 14 April 2017 |
| Primary completion | 30 December 2018 |
| Estimated completion | 22 February 2019 |
| Sites | 1 location across China |
Drugs / interventions tested
- Parenteral Nutrition — full drug profile →
Conditions studied
- Digestive System Neoplasms — all drugs for Digestive System Neoplasms →
Sponsor
Jinling Hospital, China
Who can join
Adults 18 to 80, any sex, with Digestive System Neoplasms. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients will be randomized to early PN group or late PN group at day 3 after abdominal surgery. Patients will receive supplemental parenteral nutrition or not within 7 days after abdominal surgery. Both groups will receive SPN except 80% of target energy delivered by EN or oral or patients are discharged from hospital. The primary and secondary outcomes will be collected.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Effect of Early vs Late Supplemental Parenteral Nutrition in Patients Undergoing Abdominal Surgery: A Randomized Clinical Trial.
Gao X, Liu Y, Zhang L, Zhou D, et al · · 2022 · cited 65× · PMID 35293973 · DOI 10.1001/jamasurg.2022.0269 -
Effect of early achievement of energy target by different nutritional support strategies on nosocomial infections in patients undergoing major abdominal surgery: a secondary analysis of two randomized clinical trials.
Gao X, Zhang L, Zhang Y, Zhou D, et al · · 2023 · cited 3× · PMID 37300882 · DOI 10.1097/js9.0000000000000526 -
Early enteral nutrition versus early supplemental parenteral nutrition in patients undergoing major abdominal surgery: a secondary analysis of 2 randomized clinical trials.
Gao X, Zhang Y, Qi X, Xiao Y, et al · · 2024 · cited 2× · PMID 38369126 · DOI 10.1016/j.ajcnut.2024.02.006 -
Early versus late supplemental parenteral nutrition in gastrointestinal cancer patients undergoing major abdominal surgery: 5-year outcomes from a randomized clinical trial
Gao X, Zhang Y, Xiao Y, Gao T, et al · · 2026
Verify or expand the search:
- PubMed search for NCT03115957
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Parenteral Nutrition
Trials testing the same drug.
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- NCT03926949 — Outpatient Preoperative Parenteral Nutrition in Malnourished Surgical Patients · NA · recruiting
Other recruiting trials for Digestive System Neoplasms
Currently open trials in the same condition.
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- NCT06026774 — Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms · Phase 1 · recruiting
- NCT06026800 — Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Combination With Standard First-line Treatment in Sub · Phase 1 · recruiting
- NCT06019702 — Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplas · Phase 1 · recruiting
Other Jinling Hospital, China trials
Trials by the same sponsor.
- NCT07297238 — Effect of GLP-1 on Intestinal Barrier Function in SBS-IF Patients: A Preliminary Exploration. · NA · recruiting
- NCT07237542 — Effect of Remote Ischemic Preconditioning on Early Neurological Deterioration in Acute Perforating Artery Infarction · NA · recruiting
- NCT07230314 — Sequential Transarterial Chemoembolization (TACE), Stereotactic Body Radiation Therapy (SBRT), and Immune Checkpoint Inh · Phase 2 · not yet recruiting
- NCT06177522 — Adebrelimab Combined With Chemotherapy for Neoadjuvant Therapy in Resectable Pancreatic Cancer · Phase 2 · not yet recruiting
- NCT07124624 — Stepped-Wedge Cluster Randomized Trial of AI-Assisted CTA Detection for Intracranial Aneurysms in Regional Hospitals · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03115957 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jinling Hospital, China
- Last refreshed: 29 September 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03115957.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing