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NCT03877575: LYS

Lyon Uveitis Study

Recruiting now Last updated 26 April 2024
What this trial tests

trial testing No specific intervention. Collection of clinical data in Uveitis in 750 participants. Currently enrolling.

Timeline
1 January 2016
Primary endpoint
1 January 2025
1 January 2025

Quick facts

Lead sponsorHospices Civils de Lyon
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment750
Start date1 January 2016
Primary completion1 January 2025
Estimated completion1 January 2025
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Hospices Civils de Lyon — full company profile →

Who can join

18 and older, any sex, with Uveitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Uveitis or inflammation of the uveal tract results from a heterogeneous collection of disorders of varying etiologies and pathogenic mechanisms. Uveitis is relatively frequent in industrial countries with an estimation of 115 cases for 100 000 persons and is associated with a blindness risk of 10%. Causes of uveitis can be related to different etiologies (infectious, inflammatory or general inflammatory diseases). Therapeutic care is based on ophthalmologic and systemic diagnosis and treatment strategy depends on the severity of inflammation. The main objective of the Lyon uveitis study is to analyze the uveitis ophthalmologic etiology and diagnostic and therapeutic care of the patients. This study is proposed to all patients diagnosed for uveitis and referred to the Department of Internal Medicine of the Croix Rousse hospital, Lyon, france for etiologic diagnosis or treatment. Analysis of i) patients' characteristics, ii) the relevance of complementary exams to determine the uveitis etiology, iii) treatment used. This study will allow a better characterization of the disease on diagnosis practices and therapeutic care.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Long-Term Outcomes of Birdshot Chorioretinopathy Treated with Corticosteroids: A Case Reports.
    Ferracci D, Mathis T, Gavoille A, Gerfaud-Valentin M, et al · · 2023 · cited 4× · PMID 37629330 · DOI 10.3390/jcm12165288
  2. Etiologies of intermediate uveitis in a tertiary center: an age-oriented medical assessment?
    Mansuy P, El-Jammal T, Jacquot R, Mathis T, et al · · 2025 · PMID 41389233 · DOI 10.1186/s12348-025-00563-w
  3. Hydroxychloroquine in the treatment of sarcoidosis-associated uveitis and idiopathic uveitis
    PLAVONIL S, EL-JAMMAL T, JACQUOT R, BERT A, et al · · 2024 · DOI 10.21203/rs.3.rs-4493603/v1

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Other recruiting trials for Uveitis

Currently open trials in the same condition.

Other Hospices Civils de Lyon trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03877575.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing