NCT03854929 (CIPAZ) is a Phase 4 clinical trial of Ciprofloxacin in Dysentery, Shigella, sponsored by Oxford University Clinical Research Unit, Vietnam.

Who is sponsoring NCT03854929?

NCT03854929 is sponsored by Oxford University Clinical Research Unit, Vietnam.

What drugs are being tested in NCT03854929?

Interventions in NCT03854929: Ciprofloxacin, Azithromycin.

What condition does NCT03854929 study?

NCT03854929 studies Dysentery, Shigella, Shigellosis, Diarrhea.

Is NCT03854929 still recruiting?

NCT03854929 is currently completed. Last updated 7 June 2023.

Last reviewed 2023-06-07 · How we verify

NCT03854929: CIPAZ

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery

Completed Phase 4 Last updated 7 June 2023

What this trial tests

Phase 4 trial testing Ciprofloxacin in Dysentery, Shigella in 364 participants. Completed in 12 July 2022.

Timeline

11 December 2019

Primary endpoint
6 February 2021

12 July 2022

Quick facts

Lead sponsor	Oxford University Clinical Research Unit, Vietnam
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	364
Start date	11 December 2019
Primary completion	6 February 2021
Estimated completion	12 July 2022
Sites	1 location across Vietnam

Drugs / interventions tested

Ciprofloxacin (Ciprofloxacin) — full drug profile →
Azithromycin (azithromycin) — full drug profile →

Conditions studied

Dysentery, Shigella — all drugs for Dysentery, Shigella →
Shigellosis — all drugs for Shigellosis →
Diarrhea — all drugs for Diarrhea →

Sponsor

Oxford University Clinical Research Unit, Vietnam

Who can join

Adults 6 Months to 60 Months, any sex, with Dysentery, Shigella or Shigellosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to assess the efficacy of 3 days of azithromycin (AZI) compared to 3 days of ciprofloxacin (CIP) (standard-of-care) for the treatment of children hospitalised with dysentery in Ho Chi Minh City.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The CIPAZ study protocol: an open label randomised controlled trial of azithromycin versus ciprofloxacin for the treatment of children hospitalised with dysentery in Ho Chi Minh City, Vietnam
Darton TC, Thi Hong Chau T, Parry CM, Campbell JI, et al · · 2020 · DOI 10.12688/wellcomeopenres.16093.1

Verify or expand the search:

Other trials of Ciprofloxacin

Trials testing the same drug.

NCT07492134 — APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis) · Phase 2 · not yet recruiting
NCT07016165 — Ciprofloxacin vs Ceftazidime for Empirical Treatment of High-Risk Neutropenic Fever in Children With Hematologic Maligna · Phase 4 · recruiting
NCT04791579 — Antibiotic Prophylaxis for Neurogenic Bladder Botox · Phase 2 · recruiting
NCT05846399 — CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE) · Phase 4 · recruiting
NCT05844735 — A Randomized Placebo- and Active Comparator-controlled Study to Evaluate the Photosafety of SAR441566 · Phase 1 · completed

Other recruiting trials for Dysentery, Shigella

Currently open trials in the same condition.

NCT06838195 — Clinical Trial of the S. Flexneri-S. Sonnei Bivalent Conjugate Vaccine · Phase 3 · active not recruiting

Other Oxford University Clinical Research Unit, Vietnam trials

Trials by the same sponsor.

NCT07543458 — Therapeutics for Moderate and Severe Dengue · Phase 3 · not yet recruiting
NCT06551844 — Adaptive Dengue Antiviral Platform Trial · Phase 2 · not yet recruiting
NCT05909384 — Management of Sepsis in Resource Limited Settings Using a Delphi Method. · completed
NCT05611710 — Anakinra in Dengue With Hyperinflammation ( AnaDen ) · Phase 2 · active not recruiting
NCT05083130 — Awake Prone Positioning in Moderate to Severe COVID-19 · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03854929 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Oxford University Clinical Research Unit, Vietnam
Last refreshed: 7 June 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03854929.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing