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NCT03836521
Bicuspid Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Registry
trial testing Transcatheter aortic valve replacement in Bicuspid Aortic Valve in 2,000 participants. Currently enrolling.
15 August 2028
Quick facts
| Lead sponsor | Cedars-Sinai Medical Center |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 2,000 |
| Start date | 15 August 2016 |
| Primary completion | 15 August 2028 |
| Estimated completion | 15 August 2028 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Transcatheter aortic valve replacement
Conditions studied
- Bicuspid Aortic Valve — all drugs for Bicuspid Aortic Valve →
Sponsor
Cedars-Sinai Medical Center
Who can join
Adults 19 to 129, any sex, with Bicuspid Aortic Valve. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this study is to evaluate the procedural and clinical outcomes of patients with bicuspid aortic valve stenosis undergoing transcatheter aortic valve replacement.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Bicuspid Aortic Valve Morphology and Outcomes After Transcatheter Aortic Valve Replacement.
Yoon SH, Kim WK, Dhoble A, Milhorini Pio S, et al · · 2020 · cited 203× · PMID 32854836 · DOI 10.1016/j.jacc.2020.07.005
Verify or expand the search:
- PubMed search for NCT03836521
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transcatheter aortic valve replacement
Trials testing the same drug.
- NCT07532317 — A Prospective, Multinational, Multicentre, Open-label, Randomized Trial to Evaluatesafety and Effectiveness of Meril's M · NA · not yet recruiting
- NCT06924151 — Isolated Surgical Aortic Valve Replacement in Low Risk AS Patients · NA · recruiting
- NCT06743568 — Efficacy of Self-expandable and Balloon-expandable Valves in Patients With Ascending Aortic Dilation · NA · recruiting
- NCT06589063 — Transcatheter Aortic Valve Replacement in Severe Low Flow, Low Gradient Aortic Stenosis · recruiting
- NCT06257043 — Safety and Efficacy of Post-marketing Transcatheter Aortic Valves in "Real World" Chinese Patients · recruiting
Other recruiting trials for Bicuspid Aortic Valve
Currently open trials in the same condition.
- NCT06817148 — Bicuspid Aortic Valve Replacement: Evaluation of Transcatheter Versus Surgery-Pilot Trial · NA · recruiting
- NCT05739253 — Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement · recruiting
- NCT03440697 — Pathogenetic Basis of Aortopathy and Aortic Valve Disease · active not recruiting
Other Cedars-Sinai Medical Center trials
Trials by the same sponsor.
- NCT06012487 — Correlates and Control of Blood Pressure Variability · Phase 1 · not yet recruiting
- NCT07495995 — SAMe for Prevention of Liver Cancer in MASLD-Related Cirrhosis · Phase 2 · not yet recruiting
- NCT07413965 — TAVR vs SAVR in Severe Bicuspid Aortic Stenosis · NA · not yet recruiting
- NCT06521021 — CHOICE to AVOID or RESIST · NA · not yet recruiting
- NCT07499089 — Together-Breast Cancer Support Platform · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03836521 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cedars-Sinai Medical Center
- Last refreshed: 11 February 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03836521.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing