Last reviewed · How we verify
NCT03801122: TTRAP-Bleeding
Evolution of Thromboelastography During Tranexamic Acid Treatment
Phase 2 trial testing Tranexamic acid in Hematological Malignancies Treated With Intensive Chemotherapy in 18 participants. Completed in 11 July 2022.
9 March 2022
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire de Saint Etienne |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 18 |
| Start date | 5 March 2019 |
| Primary completion | 9 March 2022 |
| Estimated completion | 11 July 2022 |
| Sites | 1 location across France |
Drugs / interventions tested
- Tranexamic acid (Tranexamic Acid) — full drug profile →
Conditions studied
- Hematological Malignancies Treated With Intensive Chemotherapy — all drugs for Hematological Malignancies Treated With Intensive Chemotherapy →
Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Who can join
18 and older, any sex, with Hematological Malignancies Treated With Intensive Chemotherapy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients with hematological malignancies are at increased risk of bleeding, especially during intensive chemotherapy. The aim of this study is to compare by thromboelastography changes during the intensive chemotherapy in patients with hematological malignancies.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Challenges and Advances in Managing Thrombocytopenic Cancer Patients.
Leader A, Hofstetter L, Spectre G. · · 2021 · cited 23× · PMID 33799591 · DOI 10.3390/jcm10061169
Verify or expand the search:
- PubMed search for NCT03801122
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Tranexamic acid
Trials testing the same drug.
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- NCT06657924 — Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery · Phase 2 · recruiting
- NCT06806241 — Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery · recruiting
- NCT06419075 — Tranexamic Acid in Vaginal Reconstructive Surgery · Phase 4 · withdrawn
Other Centre Hospitalier Universitaire de Saint Etienne trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03801122 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Saint Etienne
- Last refreshed: 6 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03801122.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing