NCT03780881: EXPECD4

EXperimental Paradigm to Investigate Expectation Change in Depression 4

Completed NA Last updated 5 December 2023

What this trial tests

NA trial testing Expectation confirmation in Major Depressive Disorder in 171 participants. Completed in 31 August 2019.

Timeline

11 November 2018

Primary endpoint
30 March 2019

31 August 2019

Quick facts

Lead sponsor	Philipps University Marburg
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	basic science
Enrollment	171
Start date	11 November 2018
Primary completion	30 March 2019
Estimated completion	31 August 2019
Sites	1 location across Germany

Drugs / interventions tested

• Expectation confirmation
• Expectation disconfirmation

Conditions studied

• Major Depressive Disorder — all drugs for Major Depressive Disorder →

Sponsor

Philipps University Marburg

Who can join

18 and older, any sex, with Major Depressive Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Research has shown that people with depressive symptoms maintain negative expectations even if they have positive experiences that contradict their expectations. Healthy people, however, change their expectations after unexpected positive experiences. In this experimental study, it will now be examined whether there are also differences between healthy people and people with depressive symptoms in dealing with unexpected negative experiences.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.