NCT03648320 (GUPI) is a NA clinical trial of Peanut oral immunotherapy in Peanut Allergy, sponsored by Guy's and St Thomas' NHS Foundation Trust.

Who is sponsoring NCT03648320?

NCT03648320 is sponsored by Guy's and St Thomas' NHS Foundation Trust.

What drugs are being tested in NCT03648320?

Interventions in NCT03648320: Peanut oral immunotherapy.

What condition does NCT03648320 study?

NCT03648320 studies Peanut Allergy.

Is NCT03648320 still recruiting?

NCT03648320 is currently completed. Last updated 29 May 2024.

Last reviewed 2024-05-29 · How we verify

NCT03648320: GUPI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Grown Up Peanut Immunotherapy Study

Completed NA Last updated 29 May 2024

What this trial tests

NA trial testing Peanut oral immunotherapy in Peanut Allergy in 33 participants. Completed in 19 May 2022.

Timeline

15 October 2018

Primary endpoint
21 May 2021

19 May 2022

Quick facts

Lead sponsor	Guy's and St Thomas' NHS Foundation Trust
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	33
Start date	15 October 2018
Primary completion	21 May 2021
Estimated completion	19 May 2022
Sites	1 location across United Kingdom

Drugs / interventions tested

Peanut oral immunotherapy — full drug profile →

Conditions studied

Peanut Allergy — all drugs for Peanut Allergy →

Sponsor

Guy's and St Thomas' NHS Foundation Trust

Who can join

Adults 18 to 40, any sex, with Peanut Allergy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To determine efficacy and safety of peanut oral immunotherapy in adults with peanut allergy.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Novel Approaches in the Inhibition of IgE-Induced Mast Cell Reactivity in Food Allergy.
Tontini C, Bulfone-Paus S. · · 2021 · cited 24× · PMID 34456900 · DOI 10.3389/fimmu.2021.613461
Oral Immunotherapy in Peanut-Allergic Adults Using Real-World Materials.
Hunter H, Ue KL, Cornelius V, Yung CC, et al · · 2025 · cited 1× · PMID 40268292 · DOI 10.1111/all.16493

Verify or expand the search:

Other trials of Peanut oral immunotherapy

Trials testing the same drug.

NCT04872218 — Adjuvant Treatment With Abatacept to Promote Remission During Peanut Oral Immunotherapy · Phase 2 · completed
NCT00932828 — Determining the Efficacy and Value of Immunotherapy on the Likelihood of Peanut Tolerance: The DEVIL Study · Phase 2 · completed

Other recruiting trials for Peanut Allergy

Currently open trials in the same condition.

NCT07349212 — UKK-0018 as an Immunotherapeutic for Treatment of Peanut Allergies · Phase 1, PHASE2 · recruiting
NCT05695261 — Evaluating the Safety and Efficacy of Oral Encapsulated Microbiota Transplantation Therapy in Peanut Allergic Patients · Phase 2 · recruiting
NCT05503446 — Using Commonly Available Food Products To Treat Food Allergy · NA · active not recruiting
NCT05667610 — Immune-supportive Diet and Gut Permeability in Allergic Children · NA · recruiting
NCT06256146 — Investigating Modified Protocols of Oral Immunotherapy to Validate Efficacy and Safety · NA · recruiting

Other Guy's and St Thomas' NHS Foundation Trust trials

Trials by the same sponsor.

NCT07534917 — Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term. · not yet recruiting
NCT07454135 — Mechanisms of Atrial Pathoelectrophysiology in HCM · not yet recruiting
NCT07419945 — Older Kidney Patient Optimisation Pretransplant · NA · not yet recruiting
NCT07309835 — Improving Genetic Medicine for Ethnic Minority Groups · not yet recruiting
NCT07203872 — Inflammation-resolution Therapy in MINST of Periodontal Intrabony Defect: a Pilot Randomised Controlled Trial · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03648320 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Guy's and St Thomas' NHS Foundation Trust
Last refreshed: 29 May 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03648320.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing