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NCT03615794

A Study of Pregnant and Postpartum Women With and Without Mood Disorders

Completed Last updated 30 December 2025
What this trial tests

trial in Bipolar Disorder in 300 participants. Completed in 6 May 2024.

Timeline
1 October 2017
Primary endpoint
31 January 2024
6 May 2024

Quick facts

Lead sponsorJohns Hopkins University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment300
Start date1 October 2017
Primary completion31 January 2024
Estimated completion6 May 2024
Sites2 locations across United States

Conditions studied

Sponsor

Johns Hopkins University

Who can join

Adults 18 to 50, any sex, with Bipolar Disorder or Major Depressive Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is looking at genetic, biological, and environmental causes and how all three may work together to cause postpartum mood episodes. Participants will have psychiatric histories taken and will be monitored throughout pregnancy and during the postpartum period for the development of depressive or other mood episodes. Biological measures, including hormone levels, immunological measures, and growth factors will be collected. Environmental factors such as sleep deprivation and stress will also be measured. These factors will be considered in the setting of genetic and epigenetic data with the hope that investigators will ultimately be able to predict the onset of postpartum mood episodes in this vulnerable population.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Bipolar Disorder

Currently open trials in the same condition.

Other Johns Hopkins University trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03615794.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing