NCT03536572: ImPRESS

Self-Management of Continuous Positive Airway Pressure Settings

Completed NA Results posted Last updated 19 September 2024

What this trial tests

NA trial testing Sleep Apnea Self-Management Program in Obstructive Sleep Apnea in 270 participants. Completed in 30 April 2023.

Timeline

1 October 2018

Primary endpoint
31 March 2023

30 April 2023

Quick facts

Lead sponsor	VA Office of Research and Development
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	supportive care
Enrollment	270
Start date	1 October 2018
Primary completion	31 March 2023
Estimated completion	30 April 2023
Sites	1 location across United States

Drugs / interventions tested

• Sleep Apnea Self-Management Program

Conditions studied

• Obstructive Sleep Apnea — all drugs for Obstructive Sleep Apnea →

Sponsor

VA Office of Research and Development — full company profile →

Who can join

Adults 18 to 70, any sex, with Obstructive Sleep Apnea. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Treatment Adherence Primary · 2 months

Measurement of the amount of time that CPAP is used on average per night over the outcome time frame

Group	Value	95% CI
Sleep Apnea Self-Management Program	2.1	± 1.5
Individualized Pressure Adjustment	2.2	± 1.6

Sponsor's own description

Obstructive sleep apnea (OSA) is a major chronic condition affecting the quality of life of millions of Americans. Per the Institute of Medicine new treatment adherence strategies are needed to help improve the quality of care, reduce social and economic costs, and help those with chronic conditions, including OSA, live healthier and more productive lives through better management of their conditions. Adherence with continuous positive airway pressure (PAP) therapy is disappointingly low, and new methods to increase both the use and efficacy of therapy are needed. Historically, patients have not been formally instructed to adjust their pressure settings on their PAP devices; practically, however, allowing patients to adjust their pressure settings fosters engagement, self-confidence, and control with therapy.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea.
   Askland K, Wright L, Wozniak DR, Emmanuel T, et al · · 2020 · cited 56× · PMID 32255210 · DOI 10.1002/14651858.cd007736.pub3