Last reviewed · How we verify
NCT03514550
Effects of Anesthesia on Immunity in Cancer
Phase 4 trial testing Propofol in Surgery in 20 participants. Completed in 20 May 2019.
1 April 2019
Quick facts
| Lead sponsor | Meshalkin Research Institute of Pathology of Circulation |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 20 |
| Start date | 14 May 2018 |
| Primary completion | 1 April 2019 |
| Estimated completion | 20 May 2019 |
| Sites | 1 location across Russia |
Drugs / interventions tested
- Propofol (Propofol) — full drug profile →
- Sevoflurane — full drug profile →
- Epidural block
Conditions studied
- Surgery — all drugs for Surgery →
- Renal Cancer — all drugs for Renal Cancer →
Sponsor
Meshalkin Research Institute of Pathology of Circulation
Who can join
18 and older, any sex, with Surgery or Renal Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the study is a comparative study of the cellular immunity response of patients operated on for kidney cancer under total intravenous and inhalational anesthesia.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The immunosuppressive effects of volatile versus intravenous anesthesia combined with epidural analgesia on kidney cancer: a pilot randomized controlled trial.
Efremov SM, Kozireva VS, Moroz GB, Abubakirov MN, et al · · 2020 · cited 6× · PMID 32098012 · DOI 10.4097/kja.19461
Verify or expand the search:
- PubMed search for NCT03514550
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT07347496 — A Randomized, Controlled Clinical Trial Comparing Remimazolam Besylate Combined With Alfentanil Versus Propofol Combined · Phase 4 · not yet recruiting
Other recruiting trials for Surgery
Currently open trials in the same condition.
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- NCT07362303 — Neuralert Stroke Monitor Trial · NA · recruiting
- NCT07404163 — Walkway Used in Postoperative Mobilization · NA · active not recruiting
- NCT07218289 — Green Light for Post-Operative Wellness · NA · recruiting
- NCT07342751 — The Effect of Listening to Music During Mobilization on Pain and Fear in Children Undergoing Abdominal Surgery · NA · active not recruiting
Other Meshalkin Research Institute of Pathology of Circulation trials
Trials by the same sponsor.
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- NCT06443931 — Cryoablation of Intercostal Nerves for Pain Management in Early Postoperative Period in Patients With Minimally Invasive · NA · completed
- NCT06069115 — Radiotherapy Exposed Lung Injury: Effect on Functioning - Cohort · recruiting
- NCT05856461 — Pulmonary Artery Denervation in Patients With Atrial Fibrillation and Group 2 of Pulmonary Hypertension · NA · unknown
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03514550 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Meshalkin Research Institute of Pathology of Circulation
- Last refreshed: 3 June 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03514550.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing