NCT05856461 (PADN+AF) is a NA clinical trial of Pulmonary vein isolation in Atrial Fibrillation, sponsored by Meshalkin Research Institute of Pathology of Circulation.

Who is sponsoring NCT05856461?

NCT05856461 is sponsored by Meshalkin Research Institute of Pathology of Circulation.

What drugs are being tested in NCT05856461?

Interventions in NCT05856461: Pulmonary vein isolation, Sham pulmonary artery denervation, Pulmonary artery denervation.

What condition does NCT05856461 study?

NCT05856461 studies Atrial Fibrillation, Pulmonary Hypertension.

Is NCT05856461 still recruiting?

NCT05856461 is currently status unknown. Last updated 25 May 2023.

Last reviewed 2023-05-25 · How we verify

NCT05856461: PADN+AF

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pulmonary Artery Denervation in Patients With Atrial Fibrillation and Group 2 of Pulmonary Hypertension

Status unknown NA Last updated 25 May 2023

What this trial tests

NA trial testing Pulmonary vein isolation in Atrial Fibrillation in 116 participants. Status unknown.

Timeline

22 May 2023

Primary endpoint
29 December 2024

22 February 2025

Quick facts

Lead sponsor	Meshalkin Research Institute of Pathology of Circulation
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	116
Start date	22 May 2023
Primary completion	29 December 2024
Estimated completion	22 February 2025
Sites	1 location across Russia

Drugs / interventions tested

Pulmonary vein isolation
Sham pulmonary artery denervation
Pulmonary artery denervation

Conditions studied

Atrial Fibrillation — all drugs for Atrial Fibrillation →
Pulmonary Hypertension — all drugs for Pulmonary Hypertension →

Sponsor

Meshalkin Research Institute of Pathology of Circulation

Who can join

Adults 18 to 80, any sex, with Atrial Fibrillation or Pulmonary Hypertension. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of the study is to compare efficacy and safety of the pulmonary artery denervation procedure combined with atrial fibrillation ablation versus atrial fibrillation ablation alone in patients with paroxysmal and persistent atrial fibrillation and group 2 of the pulmonary hypertension

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Pulmonary vein isolation

Trials testing the same drug.

NCT07450755 — Concomitant PFA Bsaed PVI Plus LAAC · NA · not yet recruiting
NCT07118046 — Comparison of Fluoroscopy-only vs. Electroanatomic Mapping Strategies for Pulmonary Vein Isolation With Balloon-based Pu · NA · recruiting
NCT06671197 — Study on the Ablation of Persistent Atrial Fibrillation Using Pulsed Electric Fields Under Different Surgical Procedures · not yet recruiting
NCT06861673 — COCONUT Study Concomitant PVI and LAAC · recruiting
NCT06096246 — Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF) · NA · recruiting

Other recruiting trials for Atrial Fibrillation

Currently open trials in the same condition.

NCT07429214 — A Study of VARIPULSE Catheter and TRUPULSE Generator With VARIPULSE Pro Software in Participants With PAF or PsAF · NA · recruiting
NCT07271238 — Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures · NA · recruiting
NCT07388108 — Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery. · recruiting
NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
NCT06650995 — AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure · NA · recruiting

Other Meshalkin Research Institute of Pathology of Circulation trials

Trials by the same sponsor.

NCT07372196 — Left Bundle Branch Pacing in Patients With Hypertrophic Cardiomyopathy After Myectomy · NA · recruiting
NCT06443931 — Cryoablation of Intercostal Nerves for Pain Management in Early Postoperative Period in Patients With Minimally Invasive · NA · completed
NCT06069115 — Radiotherapy Exposed Lung Injury: Effect on Functioning - Cohort · recruiting
NCT05643664 — The Role of Artificial Intelligence in the Treatment of Abdominal Aortic Aneurysms · NA · unknown
NCT05634018 — Comparison of the Biomechanical Properties of the Wall of an Aneurysmal-altered Abdominal Aorta According to the Results · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05856461 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Meshalkin Research Institute of Pathology of Circulation
Last refreshed: 25 May 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05856461.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing