NCT03364296 (FLAG1) is a NA clinical trial of Blood Samples in Stroke, Acute, sponsored by Central Hospital, Nancy, France.

Who is sponsoring NCT03364296?

NCT03364296 is sponsored by Central Hospital, Nancy, France.

What drugs are being tested in NCT03364296?

Interventions in NCT03364296: Blood Samples.

What condition does NCT03364296 study?

NCT03364296 studies Stroke, Acute.

Is NCT03364296 still recruiting?

NCT03364296 is currently recruiting now. Last updated 17 May 2024.

Last reviewed 2024-05-17 · How we verify

NCT03364296: FLAG1

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Biological Dating of Cerebral Ischemia With GST-π/PRDX1 to Detect Patients With Stroke of Unknown Onset Within the Therapeutic Window of Thrombolysis

Recruiting now NA Last updated 17 May 2024

What this trial tests

NA trial testing Blood Samples in Stroke, Acute in 930 participants. Currently enrolling.

Timeline

15 October 2018

Primary endpoint
13 September 2024

1 March 2025

Quick facts

Lead sponsor	Central Hospital, Nancy, France
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	930
Start date	15 October 2018
Primary completion	13 September 2024
Estimated completion	1 March 2025
Sites	5 locations across France

Drugs / interventions tested

Blood Samples — full drug profile →

Conditions studied

Stroke, Acute — all drugs for Stroke, Acute →

Sponsor

Central Hospital, Nancy, France

Who can join

18 and older, any sex, with Stroke, Acute. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The FLAG1 study will assess the diagnostic performance of biomarkers Glutathion S-Transferase-π (GST-π) and Peroxyredoxin 1 (PRDX1) to identify cerebral infarction of less than 4,5 hours in a population of patients with neurological deficiency of less than 12 hours.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Identifying patients with cerebral infarction within the time window compatible with reperfusion therapy, diagnostic performance of glutathione S-transferase-π (GST-π) and peroxiredoxin 1 (PRDX1): exploratory prospective multicentre study FLAG-1 protocol.
Karakus A, Girerd N, Sanchez JC, Sabben C, et al · · 2021 · cited 3× · PMID 34417212 · DOI 10.1136/bmjopen-2020-046167

Verify or expand the search:

Other trials of Blood Samples

Trials testing the same drug.

NCT06008990 — Maternal Brain Imaging in Opioid Use Disorder · active not recruiting
NCT05472389 — Neurodevelopmental Impact of Epilepsy on Autonomic Function in Dravet Syndrome · NA · active not recruiting
NCT05011188 — FOR46 in Combination With Enzalutamide in Patients With Metastatic Castration Resistant Prostate Cancer · Phase 1, PHASE2 · active not recruiting
NCT05020275 — Resistance to the Tyrosine Kinase Inhibitor Osimertinib and Pharmacokinetics in Non-small Cell Lung Cancer · active not recruiting
NCT05099237 — Enhanced Monitoring for Better Recovery and Cancer Experience in Greater Manchester · NA · unknown

Other recruiting trials for Stroke, Acute

Currently open trials in the same condition.

NCT06825897 — Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiograp · NA · recruiting
NCT06658197 — Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke · Phase 3 · recruiting
NCT07253870 — Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients · NA · recruiting
NCT06941753 — Off-script Diagnosis & Differential Diagnosis (D&D) Training and Residents' Stroke Knowledge · NA · recruiting
NCT06123650 — Post Stroke Dysphagia: Effect of Adding rTMS to Conventional Therapy on the Prevalence of Pneumonia. · NA · recruiting

Other Central Hospital, Nancy, France trials

Trials by the same sponsor.

NCT06452290 — PET Biomarker Study for Antidepressant Response Prediction in Major Depressive Disorder · NA · not yet recruiting
NCT07518498 — Hypnosis During Mechanical Ventilation Weaning · NA · not yet recruiting
NCT07471334 — Prospective Study of Postictal Psychotic Symptoms Occuring After Video-EEG Monitoring in Focal Epilepsies · NA · not yet recruiting
NCT07414667 — Primary Sjögren's Syndrome: Impact of Quantitative Anti-Ro52 Antibody Analysis on Patient Prognosis and Stratification ( · not yet recruiting
NCT07415759 — Imaging of Electrical Properties by MRI: Investigation of Age-Related Changes · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03364296 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Central Hospital, Nancy, France
Last refreshed: 17 May 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03364296.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing