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NCT03246594: OPERA
Oesophageal Probe Evaluation in RF Ablation of Atrial Fibrillation
NA trial testing Placement of oesophageal probe for temperature measurement in Atrial Fibrillation in 200 participants. Completed in 24 October 2019.
25 April 2019
Quick facts
| Lead sponsor | Heart Center Leipzig - University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 200 |
| Start date | 3 July 2017 |
| Primary completion | 25 April 2019 |
| Estimated completion | 24 October 2019 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Placement of oesophageal probe for temperature measurement
- Power limitation of RF generator
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
Sponsor
Heart Center Leipzig - University Hospital
Who can join
Adults 18 to 85, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The Trial will evaluate the influence of oesophageal probes in Radio frequency (RF)-ablation of atrial fibrillation regarding oesophageal ulcers after ablation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Oesophageal Probe Evaluation in Radiofrequency Ablation of Atrial Fibrillation (OPERA): results from a prospective randomized trial.
Schoene K, Arya A, Grashoff F, Knopp H, et al · · 2020 · cited 68× · PMID 32820324 · DOI 10.1093/europace/euaa209
Verify or expand the search:
- PubMed search for NCT03246594
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Atrial Fibrillation
Currently open trials in the same condition.
- NCT07429214 — A Study of VARIPULSE Catheter and TRUPULSE Generator With VARIPULSE Pro Software in Participants With PAF or PsAF · NA · recruiting
- NCT07271238 — Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures · NA · recruiting
- NCT07388108 — Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery. · recruiting
- NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
- NCT06650995 — AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure · NA · recruiting
Other Heart Center Leipzig - University Hospital trials
Trials by the same sponsor.
- NCT07462624 — REpeat Intervention For Failed Surgical BioProsthEtic AorTic Valves (REPEAT) · NA · recruiting
- NCT06845579 — Prediction of Blood Pressure Outcomes Following Renal Denervation (PREDICT-RDN) · NA · recruiting
- NCT07049289 — Telemonitoring in Arterial Hypertension · NA · active not recruiting
- NCT04737317 — Diagnostic Criteria in Cardiac Sarcoidosis · recruiting
- NCT05793398 — Biomaterial Collection - and Analysis in Cardiac Sarcoidosis · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03246594 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Heart Center Leipzig - University Hospital
- Last refreshed: 20 May 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03246594.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing