Who is sponsoring NCT03095976?

NCT03095976 is sponsored by Indiana University.

What condition does NCT03095976 study?

NCT03095976 studies Periodontal Diseases.

Is NCT03095976 still recruiting?

NCT03095976 is currently completed. Last updated 14 April 2021.

Are results published for NCT03095976?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2021-04-14 · How we verify

NCT03095976

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Amnion-Chorion Allograft Barrier Used for Root Surface and Guided Tissue Regeneration

Completed NA Results posted Last updated 14 April 2021

What this trial tests

NA trial testing Amnion-Chorion allograft membrane on the root surface of periodontally diseased site. in Periodontal Diseases in 4 participants. Completed in 10 September 2019.

Timeline

14 June 2017

Primary endpoint
10 September 2019

10 September 2019

Quick facts

Lead sponsor	Indiana University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	4
Start date	14 June 2017
Primary completion	10 September 2019
Estimated completion	10 September 2019
Sites	1 location across United States

Drugs / interventions tested

Amnion-Chorion allograft membrane on the root surface of periodontally diseased site.

Conditions studied

Periodontal Diseases — all drugs for Periodontal Diseases →

Sponsor

Indiana University

Who can join

Adults 18 to 75, any sex, with Periodontal Diseases. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Probing Depth Change Primary · Baseline and 6 months

Probing depth was measured at intrabony defect following surgical procedure.

Group	Value	95% CI
Test Group	4.22	± 0.73

Clinical Attachment Change Primary · Baseline and 6 months

Clinical Attachment is defined as the sum of probing depth and gingival recession. The amount of gain of attachment level will be measured.

Group	Value	95% CI
Test Group	2.44	± 2.24

Sponsor's own description

The purpose of this pilot project is to evaluate the efficacy of application of Amnion-Chorion allograft membrane on the root surface of periodontally diseased teeth in conjunction with bone substitute covered by Amnion-Chorion allograft in a combination Guided Tissue Regeneration (GTR) treatment of periodontal intrabony and furcation defects.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Periodontal Diseases

Currently open trials in the same condition.

NCT07358104 — Efficacy of Camel Whey Protein and Camel Whey Protein Nanoparticles for Treating Intra-bony Periodontal Defects · NA · active not recruiting
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NCT07384221 — Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients · recruiting
NCT07530978 — ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE · recruiting
NCT06848790 — Interdental Hygiene Methods in Young Adults · NA · recruiting

Other Indiana University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03095976 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Indiana University
Last refreshed: 14 April 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03095976.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing