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NCT03068260
Ultrasound-guided Transmuscular Quadratus Lumborum Block for Elective Caesarean Section.
Phase 4 trial testing Ropivacaine in Postoperative Pain in 72 participants. Completed in 1 December 2017.
1 December 2017
Quick facts
| Lead sponsor | Zealand University Hospital |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 72 |
| Start date | 15 March 2017 |
| Primary completion | 1 December 2017 |
| Estimated completion | 1 December 2017 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Ropivacaine (ROPIVACAINE) — full drug profile →
- Saline
- Acetaminophen (Paracetamol) — full drug profile →
- Ibuprofen 400Mg Tablet / Celebra 100 Mg tablet — full drug profile →
- ultrasound-guided nerve block
- Morphine
- Patient-controlled analgesia
Conditions studied
- Postoperative Pain — all drugs for Postoperative Pain →
Sponsor
Zealand University Hospital
Who can join
Adults 18 to 100, female only, with Postoperative Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
ECS is a very common procedure. A 1-year retrospective survey revealed a vast opioid consumption among the new mothers of approximately (mean±SD) 35±25 mg of oral morphine in the first 24 postoperative hours despite a multimodal analgesic regimen. The adverse effects of morphine are well known and include postoperative nausea and vomiting (PONV), itching, fatigue, constipation, confusion, respiratory depression and delayed mobilization. These adverse effects are unsound for the new mothers as well as the breast-fed, newborn children. This study aims to evaluate the efficacy of bilateral Transmuscular Quadratus Lumborum (TQL) block in reducing postoperative morphine consumption and pain.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Abdominal wall blocks for intra-abdominal surgery.
Onwochei DN, Børglum J, Pawa A. · · 2018 · cited 22× · PMID 33456796 · DOI 10.1016/j.bjae.2018.07.002
Verify or expand the search:
- PubMed search for NCT03068260
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Postoperative Pain
Currently open trials in the same condition.
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Other Zealand University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03068260 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zealand University Hospital
- Last refreshed: 23 March 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03068260.
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