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NCT07373561: PICAS-DK
Post-Intensive Care Syndrome and Associated Symptom Burden Among Danish ICU Survivors
trial in Post-Intensive Care Syndrome (PICS) in 800 participants. Not yet recruiting.
30 June 2028
Quick facts
| Lead sponsor | Zealand University Hospital |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 800 |
| Start date | 1 June 2026 |
| Primary completion | 30 June 2028 |
| Estimated completion | 30 September 2028 |
Conditions studied
- Post-Intensive Care Syndrome (PICS) — all drugs for Post-Intensive Care Syndrome (PICS) →
- Symptom Burden — all drugs for Symptom Burden →
- Intensive Care Unit (ICU) Patients — all drugs for Intensive Care Unit (ICU) Patients →
Sponsor
Zealand University Hospital
Who can join
18 and older, any sex, with Post-Intensive Care Syndrome (PICS) or Symptom Burden. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study aims to estimate the prevalence of post-intensive care syndrome (PICS) 12 months after ICU admission among adult ICU survivors in Denmark and to describe how this prevalence is distributed across the physical, cognitive, and mental health domains. By conducting follow-up assessments at 3, 6, and 12 months post-discharge, the study further seeks to determine the prevalence of PICS at each time point, characterise its temporal trajectory, and explore patients' symptom burden over time. Research question * What is the prevalence of PICS and its specific components (physical, cognitive, and mental health domains) among ICU survivors 12 months after ICU admission? * How do the components of PICS evolve during the follow-up period (trajectory)? * What risk factors are associated with the development of PICS in ICU survivors? * Are there differences in PICS prevalence based on demographic or clinical characteristics (e.g., age, comorbidities, ICU length of stay)? The hypothesis is that the prevalence of post-intensive care syndrome (PICS) in a Danish cohort of adult ICU survivors at 12 months will be approximately one third, defined as impairment in at least one of the three PICS domains (physical, cognitive, or mental health), measured using validated instruments with pre-specified cut-offs.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07373561
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Post-Intensive Care Syndrome (PICS)
Currently open trials in the same condition.
- NCT07170527 — Long-Term Outcomes and Post-Intensive Care Syndrome: Investigating the Associations Between Metabolic Signatures and Phy · recruiting
- NCT07035106 — I-WEAR: Evaluating Wearables and Health Summaries in ICU Survivors · NA · recruiting
Other Zealand University Hospital trials
Trials by the same sponsor.
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- NCT07365527 — Sonoporation and Tumor Microenvironment Response in Colorectal Liver Metastases · NA · recruiting
- NCT07304375 — Effects of Exercise and Sleep on Motor Learning and Functional Abilities in Multiple Sclerosis · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07373561 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zealand University Hospital
- Last refreshed: 30 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07373561.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing