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NCT03007121: KOLORIT
Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.
Phase 4 trial testing Morphine intrathecal in Analgesia, Patient-Controlled in 75 participants. Completed in 17 December 2018.
14 December 2018
Quick facts
| Lead sponsor | Charles University, Czech Republic |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 75 |
| Start date | 10 April 2017 |
| Primary completion | 14 December 2018 |
| Estimated completion | 17 December 2018 |
| Sites | 1 location across Czechia |
Drugs / interventions tested
- Morphine intrathecal — full drug profile →
- Bupivacaine + Sufentanil epidural — full drug profile →
- Morphine intravenous — full drug profile →
Conditions studied
- Analgesia, Patient-Controlled — all drugs for Analgesia, Patient-Controlled →
- Epidural Analgesia — all drugs for Epidural Analgesia →
- Anesthesia; Spinal — all drugs for Anesthesia; Spinal →
- Morphine — all drugs for Morphine →
Sponsor
Charles University, Czech Republic
Who can join
18 and older, any sex, with Analgesia, Patient-Controlled or Epidural Analgesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to determine which postoperative analgesia is optimal after colorectal surgery. The investigators will compare intrathecal morphine, continuous epidural analgesia and standard systemic analgesia. All patients will have the possibility to administer themselves intravenous morphine as needed.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03007121
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Morphine intrathecal
Trials testing the same drug.
- NCT06715657 — Effect of Propofol Administration Time on the Incidence and Severity of Intrathecal Morphine-induced Pruritus in Parturi · Phase 4 · not yet recruiting
Other recruiting trials for Analgesia, Patient-Controlled
Currently open trials in the same condition.
- NCT05672225 — Two-channel IV-PCA With Dexmedetomidine · NA · recruiting
Other Charles University, Czech Republic trials
Trials by the same sponsor.
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- NCT07512570 — Feasibility and Preliminary Effects of a Structured Resistance Training Program in Children Aged 10-14 Years · NA · not yet recruiting
- NCT07424326 — Extended Ablation Versus Pulmonary Vein Isolation to Treat Persistent Atrial Fibrillation · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03007121 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Charles University, Czech Republic
- Last refreshed: 31 January 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03007121.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing