NCT02522858 is a Phase 4 clinical trial of Atropine in Bradycardia, sponsored by Sira Bang.

Who is sponsoring NCT02522858?

NCT02522858 is sponsored by Sira Bang.

What drugs are being tested in NCT02522858?

Interventions in NCT02522858: Atropine, Dexmedetomidine, Ephedrine.

What condition does NCT02522858 study?

NCT02522858 studies Bradycardia.

Is NCT02522858 still recruiting?

NCT02522858 is currently completed. Last updated 14 January 2016.

Last reviewed 2016-01-14 · How we verify

NCT02522858

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Anticholinergic Premedication for Sedation With Dexmedetomidine During Spinal Anesthesia

Completed Phase 4 Last updated 14 January 2016

What this trial tests

Phase 4 trial testing Atropine in Bradycardia in 120 participants. Completed in 1 January 2016.

Timeline

1 August 2015

Primary endpoint
1 January 2016

1 January 2016

Quick facts

Lead sponsor	Sira Bang
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	120
Start date	1 August 2015
Primary completion	1 January 2016
Estimated completion	1 January 2016
Sites	1 location across South Korea

Drugs / interventions tested

Atropine (ATROPINE) — full drug profile →
Dexmedetomidine (dexmedetomidine) — full drug profile →
Ephedrine (EPHEDRINE) — full drug profile →

Conditions studied

Bradycardia — all drugs for Bradycardia →

Sponsor

Sira Bang

Who can join

20 and older, any sex, with Bradycardia. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

The incidence of bradycardia
Time frame: 30miniutes from starting dexmedetomidine with loading dose
The heart rate decreasing 30% from initial heart rate or under 40/min would be regarded as bradycardia needing treatment, and atropine 0.5mg will be injected intravenously.

Sponsor's own description

Dexmedetomidine is a selective α2 adrenergic receptor antagonist, which has little effect on respiratory suppression used as sedative agent. Also, dexmedetomidine has been reported to prolong the anesthesia time when used with patients undergoing spinal anesthesia. However, dexmedetomidine has sympathetic effect which can cause hypotension and bradycardia dose dependently. Therefore, this study is aimed to evaluate the effectiveness of premedication of anticholinergic agents on vital sign in patients undergoing spinal anesthesia.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Atropine

Trials testing the same drug.

NCT07095894 — A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia Control · Phase 3 · not yet recruiting
NCT05815784 — Myopia Control: a Comparison Study Between Atropine and MiSight · Phase 2 · recruiting
NCT06111352 — Outcome of Moderate Severity in OPC Poisoning Patients When Treated With Pralidoxime · Phase 2 · completed
NCT05203432 — Red Light Intervention on Myopic Progression · NA · unknown
NCT04699357 — The Effect and Safety of Different Doses of Atropine on Myopic Progression of Highly Myopic Children: Multi-centered Ran · NA · completed

Other recruiting trials for Bradycardia

Currently open trials in the same condition.

NCT07209852 — Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-up · recruiting
NCT07254013 — Left Bundle Branch Area Pacing (LBBAP) Monitoring Assistant: Evaluation of Portable ECG Solution · NA · recruiting
NCT07166614 — Dexmedetomidine vs Propofol in High-Risk ERCP Patients · NA · recruiting
NCT07585799 — Permanent Conduction System Pacing Versus Atrioventricular Management for Patients With Wide QRS and Patent AV Conductio · NA · recruiting
NCT07217392 — Left Bundle Branch Area Pacing (LBBAP) PMCF Study · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02522858 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Sira Bang
Last refreshed: 14 January 2016

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02522858.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing