NCT02299947 (FIBTEG) is a Phase 4 clinical trial of Haemocomplettan P in Hemorrhage, sponsored by St. Antonius Hospital.

Who is sponsoring NCT02299947?

NCT02299947 is sponsored by St. Antonius Hospital.

What drugs are being tested in NCT02299947?

Interventions in NCT02299947: Haemocomplettan P, Placebo.

What condition does NCT02299947 study?

NCT02299947 studies Hemorrhage, Thoracic Aneurysm.

Is NCT02299947 still recruiting?

NCT02299947 is currently terminated. Last updated 10 May 2019.

Last reviewed 2019-05-10 · How we verify

NCT02299947: FIBTEG

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Bloodtranfusions After Aortic Surgery

Terminated Phase 4 Last updated 10 May 2019

What this trial tests

Phase 4 trial testing Haemocomplettan P in Hemorrhage in 27 participants. Terminated before completion.

Timeline

1 August 2014

Primary endpoint
26 April 2018

26 April 2018

Quick facts

Lead sponsor	St. Antonius Hospital
Phase	Phase 4
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	27
Start date	1 August 2014
Primary completion	26 April 2018
Estimated completion	26 April 2018
Sites	1 location across Netherlands

Drugs / interventions tested

Haemocomplettan P
Placebo

Conditions studied

Hemorrhage — all drugs for Hemorrhage →
Thoracic Aneurysm — all drugs for Thoracic Aneurysm →

Sponsor

St. Antonius Hospital

Who can join

18 and older, any sex, with Hemorrhage or Thoracic Aneurysm. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to answer the following question: Leads a primary coagulation corrected with a single dose of fibrinogen concentrate after ascending aorta-arc reconstruction to a decrease in the number of allogenic blood transfusions, compared to placebo?

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Pro-coagulant haemostatic factors for the prevention and treatment of bleeding in people without haemophilia.
Fabes J, Brunskill SJ, Curry N, Doree C, et al · · 2018 · cited 11× · PMID 30582172 · DOI 10.1002/14651858.cd010649.pub2
Does Intraoperative Fibrinogen Affect Blood Loss or Transfusion Practice After Aortic Arch Surgery: A Prematurely Ended Randomized Trial.
Vlot EA, Hackeng CM, Aper SJA, Sonker U, et al · · 2022 · cited 1× · PMID 36476152 · DOI 10.1177/10760296221144042

Verify or expand the search:

Other recruiting trials for Hemorrhage

Currently open trials in the same condition.

NCT07311343 — Oral Hygiene and Prophylactic Antibiotics to Prevent Intracerebral Hemorrhage Associated Pneumonia · Phase 4 · recruiting
NCT07105904 — Biological and Clinical Relevance of Quantra Viscoelastic Hemostatic Assay in Hemorrhagic Cardiac Surgery · active not recruiting
NCT06979466 — Q Therapeutic System for Chronic Stroke Recovery · NA · recruiting
NCT06664775 — A Study to Compare the Efficacy and Safety of TachoSil and Surgicel Original as an Adjunct to Control Mild to Moderate S · Phase 3 · recruiting
NCT06304714 — Effects of Bothrops Spp. Snake Envenomation on Willebrand Factor Activity in Martinique and French Guiana · recruiting

Other St. Antonius Hospital trials

Trials by the same sponsor.

NCT07398118 — CRYO-1: Cryoablation in Elderly Patients With Early-Stage Breast Cancer. · NA · not yet recruiting
NCT07414446 — Non-Invasive Detection of Pulmonary Right-to-Left Shunts Using the SONAS Ultrasound Device · NA · recruiting
NCT07309848 — Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs · recruiting
NCT07157358 — Online Medical Hypnosis Exercises to Improve Mental Health in Primary School Children and Prevent Future Mental Health I · NA · recruiting
NCT06960174 — Virtual Renality: Assessing the Impact of Virtual Reality on Preoperative Planning in Renal Cancer Surgery · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02299947 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by St. Antonius Hospital
Last refreshed: 10 May 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02299947.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing